Evidence map›Paper›PMID 28701438›Full record

ReviewCanadian family physician Medecin de famille canadien2017

Community-associated methicillin-resistant

Kassandra Loewen, Yoko Schreiber, Mike Kirlew, Natalie Bocking, Len Kelly

Erratum issuedAbstract readReview
In one paragraph

Review in Canadian family physician Medecin de famille canadien, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 96 citations in OpenAlex.

  1. The global epidemiology of MRSA.JAC-antimicrobial resistance · 2026
    Review
  2. Staphylococcal Cassette ChromosomeAntibiotics (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Healthcare-associated infections and antimicrobial resistance in Canadian acute care hospitals, 2019-2023.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  11. Article
  12. Decolonization of methicillin-resistantAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025
    Article
  13. Article
  14. Novel Tricyclic Flavonoids as Promising Anti-MRSA Agents.Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  15. Article
  16. Healthcare-associated infections and antimicrobial resistance in Canadian acute care hospitals, 2018-2022.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024
    Article
  17. Article
  18. Article
  19. Antimicrobial Resistance Patterns in an Urban County: a Spatiotemporal Exploration.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 5 countries.

Kassandra LoewenResearch intern in the Anishinaabe Bimaadiziwin Research Program in Sioux Lookout, Ont.
Yoko SchreiberAssistant Professor at the University of Ottawa in the Ottawa Hospital in Ontario, Clinical Investigator in the Ottawa Hospital Research Institute, and a visiting faculty member at the Northern Ontario School of Medicine in Sioux Lookout.
Mike KirlewAssistant Professor at the Northern Ontario School of Medicine and a community physician in Sioux Lookout.
Natalie BockingPublic health physician in the Sioux Lookout First Nations Health Authority.
Len KellyResearch consultant for the Anishinaabe Bimaadiziwin Research Program. lkelly@mcmaster.ca.
Health First · USInoue Hospital · JPMammal Research Institute · PLNOSM University · CAOttawa Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo provide information on the prevalence and treatment of methicillin-resistant QUALITY OF EVIDENCE: The MEDLINE and EMBASE databases were searched from 2005 to 2016. Epidemiologic studies were summarized and the relevant treatment literature was based on level I evidence. MAIN MESSAGE: The incidence of community-associated MRSA infection is rising. Certain populations, including indigenous Canadians and homeless populations, are particularly affected. Community-associated MRSA can be distinguished from health care-associated MRSA based on genetic, epidemiologic, or microbiological profiles. It retains susceptibility to some oral agents including trimethoprim-sulfamethoxazole, clindamycin, and tetracyclines. Community-associated MRSA typically presents as purulent skin and soft tissue infection, but invasive infection occurs and can lead to severe, complicated disease. Treatment choices and the need for empiric MRSA coverage are influenced by the type and severity of infection.

conclusionCommunity-associated MRSA is a common cause of skin and soft tissue infections and might be common in populations where overcrowding and limited access to clean water exist.

Indexed as

Administration, OralAnti-Bacterial AgentsCanadaCommunity-Acquired InfectionsHumansMethicillin-Resistant Staphylococcus aureusRandomized Controlled Trials as TopicSoft Tissue InfectionsStaphylococcal Skin InfectionsTrimethoprim, Sulfamethoxazole Drug CombinationAnti-Bacterial AgentsTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID28701438
PMCPMC5507223
OpenAlexW2948572687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.