Evidence map›Paper›PMID 28701427›Full record

ArticlePediatrics2017

Controlling Phlebotomy Volume Diminishes PICU Transfusion: Implementation Processes and Impact.

Katherine Steffen, Allan Doctor, Julie Hoerr, Jeff Gill, Chris Markham, Sarah M Brown, Daniel Cohen, Rose Hansen, Emily Kryzer, Jessica Richards and 5 more

Abstract read
In one paragraph

Article in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. The Pursuit of Quality for Social Work Practice: Three Generations and Counting.Journal of the Society for Social Work and Research · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Katherine SteffenDivision of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri; steffen.kate@gmail.com.
Allan DoctorDivision of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.
Julie HoerrDivision of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.
Jeff GillDepartment of Political Science.
Chris MarkhamDivision of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.
Sarah M BrownDivision of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.
Daniel CohenCollege of Arts and Sciences, and.
Rose HansenDivision of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.
Emily KryzerGeorge Warren Brown School of Social Work, Washington University in St Louis, St Louis, Missouri; and.
Jessica RichardsDivision of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.
Sara SmallDivision of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.
Stacey ValentineDepartment of Anesthesia, Harvard University, Children's Hospital Boston, Boston, Massachusetts.
Jennifer L YorkDivision of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.
Enola K ProctorGeorge Warren Brown School of Social Work, Washington University in St Louis, St Louis, Missouri; and.
Philip C SpinellaDivision of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
SEPSIS-INDUCED RED CELL DYSFUNCTION (SIRD)R01GM113838 · NIGMS · WASHINGTON UNIVERSITY · PI DOCTOR, ALLAN, MCMAHON, TIMOTHY J · 2015 to 2019
$4.0M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NIGMS NIH HHS R01 GM113838
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPhlebotomy excess contributes to anemia in PICU patients and increases the likelihood of red blood cell transfusion, which is associated with risk of adverse outcomes. Excessive phlebotomy reduction (EPR) strategies may reduce the need for transfusion, but have not been evaluated in a PICU population. We hypothesized that EPR strategies, facilitated by implementation science methods, would decrease excess blood drawn and reduce transfusion frequency.

methodsQuantitative and qualitative methods were used. Patient and blood draw data were collected with survey and focus group data to evaluate knowledge and attitudes before and after EPR intervention. The Consolidated Framework for Implementation Research was used to interpret qualitative data. Multivariate regression was employed to adjust for potential confounders for blood overdraw volume and transfusion incidence.

resultsPopulations were similar pre- and postintervention. EPR strategies decreased blood overdraw volumes 62% from 5.5 mL (interquartile range 1-23) preintervention to 2.1 mL (interquartile range 0-7.9 mL) postintervention (

conclusionsImplementation science methods aided in the selection of EPR strategies and enhanced acceptance which, in this cohort, reduced excessive overdraw volumes and transfusion frequency. Larger trials are needed to determine if this approach can be applied in broader PICU populations.

Indexed as

Unnecessary ProceduresAnemiaBlood VolumeChildChild, PreschoolErythrocyte TransfusionFemaleHealth Plan ImplementationHematocritHemoglobinometryHumansInfantInservice TrainingIntensive Care Units, PediatricMaleMissouri

Identifiers

PMID28701427
PMCPMC5527666

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.