Evidence map›Paper›PMID 28701381›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Enhanced coupling of light into a turbid medium through microscopic interface engineering.

Jonathan V Thompson, Brett H Hokr, Wihan Kim, Charles W Ballmann, Brian E Applegate, Javier Jo, Alexey Yamilov, Hui Cao, Marlan O Scully, Vladislav V Yakovlev

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jonathan V ThompsonInstitute for Quantum Science and Engineering, Texas A&M University, College Station, TX 77843.
Brett H HokrInstitute for Quantum Science and Engineering, Texas A&M University, College Station, TX 77843.
Wihan KimDepartment of Biomedical Engineering, Texas A&M University, College Station, TX 77843.
Charles W BallmannInstitute for Quantum Science and Engineering, Texas A&M University, College Station, TX 77843.
Brian E ApplegateDepartment of Biomedical Engineering, Texas A&M University, College Station, TX 77843.
Javier JoDepartment of Biomedical Engineering, Texas A&M University, College Station, TX 77843.
Alexey YamilovDepartment of Physics, Missouri University of Science & Technology, Rolla, MO 65409.
Hui CaoDepartment of Applied Physics, Yale University, New Haven, CT 06520.
Marlan O ScullyInstitute for Quantum Science and Engineering, Texas A&M University, College Station, TX 77843; scully@tamu.edu.
Vladislav V YakovlevDepartment of Biomedical Engineering, Texas A&M University, College Station, TX 77843.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are many optical detection and sensing methods used today that provide powerful ways to diagnose, characterize, and study materials. For example, the measurement of spontaneous Raman scattering allows for remote detection and identification of chemicals. Many other optical techniques provide unique solutions to learn about biological, chemical, and even structural systems. However, when these systems exist in a highly scattering or turbid medium, the optical scattering effects reduce the effectiveness of these methods. In this article, we demonstrate a method to engineer the geometry of the optical interface of a turbid medium, thereby drastically enhancing the coupling efficiency of light into the material. This enhanced optical coupling means that light incident on the material will penetrate deeper into (and through) the medium. It also means that light thus injected into the material will have an enhanced interaction time with particles contained within the material. These results show that, by using the multiple scattering of light in a turbid medium, enhanced light-matter interaction can be achieved; this has a direct impact on spectroscopic methods such as Raman scattering and fluorescence detection in highly scattering regimes. Furthermore, the enhanced penetration depth achieved by this method will directly impact optical techniques that have previously been limited by the inability to deposit sufficient amounts of optical energy below or through highly scattering layers.

Indexed as

enhanced transmittanceoptical couplingoptical scatteringspectroscopyturbid media

Identifiers

PMID28701381
PMCPMC5544321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.