GuidelineEvidence-based medicine2017
Guidelines for reporting meta-epidemiological methodology research.
Guideline in Evidence-based medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 208 papers, 41 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
208 citing papers in PubMed, 41 syntheses or guidelines pooled it.
- The efficacy of prophylactic tranexamic acid in patients with hematologic malignancy: a systematic review and meta-analysis.International journal of hematology · 2026Pooled it
- Evaluating Reporting Completeness in Oral Health Clinical Guidelines: A Meta-Research Study.JDR clinical and translational research · 2026Pooled it
- Application of variance ratios to assess heterogeneity of spinal manipulative therapy for chronic low back pain: A meta-epidemiological study.PM & R : the journal of injury, function, and rehabilitation · 2026Pooled it
- Characteristics of studies falsely excluded during single-reviewer abstract screening: a meta-epidemiological analysis.BMC medical research methodology · 2026Pooled it
- Impact of Different Dosage Forms of Orally Administered Chinese Herbal Medicine on Treatment and Adverse Effect Estimates in Randomized Controlled Trials: A Meta-Epidemiological Study.Journal of evidence-based medicine · 2026Pooled it
- Pooled it
- Methodological rigour and reporting quality of the literature on wildlife rescue, rehabilitation, and release: a global systematic review.The veterinary quarterly · 2025Pooled it
- Research without prior consent procedure and intervention effect on mortality in critical care: a meta-epidemiological study of randomized controlled trials.Critical care (London, England) · 2025Pooled it
- Racial, ethnic, sex, and age representation in clinical trials of radiopharmaceutical tumor therapy: a systematic review and meta-analysis.BMC cancer · 2025Pooled it
- Reporting Quality of AI Intervention in Randomized Controlled Trials in Primary Care: Systematic Review and Meta-Epidemiological Study.Journal of medical Internet research · 2025Pooled it
- Evidence certainty in neonatology-a meta-epidemiological analysis of Cochrane reviews.European journal of pediatrics · 2025Pooled it
- Evaluating agreement between individual nutrition randomised controlled trials and cohort studies - a meta-epidemiological study.BMC medicine · 2025Pooled it
- Reporting and methodological quality of systematic reviews underpinning clinical practice guidelines for low back pain: a meta-epidemiological study.Frontiers in pain research (Lausanne, Switzerland) · 2025Pooled it
- Characterising umbrella reviews in paediatrics: A systematic analysis.Acta paediatrica (Oslo, Norway : 1992) · 2025Pooled it
- Treatment Effects in Randomized and Nonrandomized Studies of Pharmacological Interventions: A Meta-Analysis.JAMA network open · 2024Pooled it
- Underserved groups could be better considered within population-based eye health surveys: a methodological study.Journal of clinical epidemiology · 2024Pooled it
- User engagement in clinical trials of digital mental health interventions: a systematic review.BMC medical research methodology · 2024Pooled it
- Quantitative assessment of baseline imbalances in evolocumab and alirocumab trials: a meta-epidemiological study.BMC medical research methodology · 2024Pooled it
- A systematic meta-epidemiologic review on nonabstinence-inclusive interventions for substance use: inclusion of race/ethnicity and sex assigned at birth/gender.The American journal of drug and alcohol abuse · 2024Pooled it
- Statin Use and Liver Cancer Risk: A Meta-Epidemiological Study of Retrospective Cohort Studies by the Types of Constructed Cohort.Asian Pacific journal of cancer prevention : APJCP · 2024Pooled it
148 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Published research should be reported to evidence users with clarity and transparency that facilitate optimal appraisal and use of evidence and allow replication by other researchers. Guidelines for such reporting are available for several types of studies but not for meta-epidemiological methodology studies. Meta-epidemiological studies adopt a systematic review or meta-analysis approach to examine the impact of certain characteristics of clinical studies on the observed effect and provide empirical evidence for hypothesised associations. The unit of analysis in meta-epidemiological studies is a study, not a patient. The outcomes of meta-epidemiological studies are usually not clinical outcomes. In this guideline, we adapt items from the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) to fit the context of meta-epidemiological studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.