Evidence map›Paper›PMID 28701357›Full record

ArticleAmerican journal of physiology. Cell physiology2017

A tale of two niches: differential functions for VCAM-1 in satellite cells under basal and injured conditions.

Hyo-Jung Choo, James P Canner, Katherine E Vest, Zachary Thompson, Grace K Pavlath

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Resistance-based exercise restores muscle health in dialysis patients.Journal of muscle research and cell motility · 2026
    Article
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  14. Review
  15. Stem Cell and Macrophage Roles in Skeletal Muscle Regenerative Medicine.International journal of molecular sciences · 2021
    Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hyo-Jung ChooDepartment of Pharmacology, Emory University, Atlanta, Georgia; and.
James P CannerDepartment of Pharmacology, Emory University, Atlanta, Georgia; and.
Katherine E VestDepartment of Pharmacology, Emory University, Atlanta, Georgia; and.
Zachary ThompsonDepartment of Pharmacology, Emory University, Atlanta, Georgia; and.
Grace K PavlathDepartment of Pharmacology, Emory University, Atlanta, Georgia; and gpavlat@emory.edu.
Emory University · US

Funding

Olfactory receptor signaling in skeletal muscleR01AR061267 · NIAMS · EMORY UNIVERSITY · PI PAVLATH, GRACE K · 2012 to 2016
$1.7M
Myogenesis and RNA Biogenesis in a Mouse Model of OPMDF32AR068207 · NIAMS · EMORY UNIVERSITY · PI VEST, KATHERINE ELIZABETH · 2016 to 2018
$150k
NIAMS NIH HHS F32 AR068207NIAMS NIH HHS R01 AR061267
6 · The paper itself

Abstract

Cell-cell adhesion molecules play key roles in maintaining quiescence or promoting activation of various stem cells in their niche. Muscle stem cells called satellite cells (SC) are critical for skeletal muscle regeneration after injury, but little is known about the role of adhesion molecules in regulating the behavior of these stem cells. Vascular cell adhesion molecule-1 (VCAM-1) is a cell-cell adhesion protein expressed on quiescent and activated SC whose function is unknown in this context. We deleted

Indexed as

Stem Cell NicheAnimalsCells, CulturedCell SurvivalFemaleMaleMiceMice, Inbred C57BLMice, KnockoutMuscle, SkeletalRegenerationSatellite Cells, Skeletal MuscleVascular Cell Adhesion Molecule-1Vascular Cell Adhesion Molecule-1AktapoptosisfusionmuscleVLA-4

Identifiers

PMID28701357
PMCPMC5668577
OpenAlexW2736098679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.