Evidence map›Paper›PMID 28701347›Full record

ArticleMolecular biology of the cell2017

A casein kinase 1 prevents expulsion of the oocyte meiotic spindle into a polar body by regulating cortical contractility.

Jonathan R Flynn, Francis J McNally

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cortical microtubules oppose actomyosin-driven membrane ingression duringbioRxiv : the preprint server for biology · 2023
    Article
  5. Article
  6. Going with the flow: insights fromPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jonathan R FlynnDepartment of Molecular and Cellular Biology, University of California, Davis, Davis, CA 95616.
Francis J McNallyDepartment of Molecular and Cellular Biology, University of California, Davis, Davis, CA 95616 fjmcnally@ucdavis.edu.
University of California, San Francisco · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Mechanisms of asymmetric cell division during female meiosis.R01GM079421 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MCNALLY, FRANCIS J · 2007 to 2019
$3.8M
NIGMS NIH HHS R01 GM079421NIH HHS P40 OD010440
6 · The paper itself

Abstract

During female meiosis, haploid eggs are generated from diploid oocytes. This reduction in chromosome number occurs through two highly asymmetric cell divisions, resulting in one large egg and two small polar bodies. Unlike mitosis, where an actomyosin contractile ring forms between the sets of segregating chromosomes, the meiotic contractile ring forms on the cortex adjacent to one spindle pole, then ingresses down the length of the spindle to position itself at the exact midpoint between the two sets of segregating chromosomes. Depletion of casein kinase 1 gamma (CSNK-1) in

Indexed as

ActinsAnimalsAsymmetric Cell DivisionCaenorhabditis elegansCaenorhabditis elegans ProteinsCasein Kinase IChromosomesContractile ProteinsCytokinesisFemaleMeiosisMitosisMyosinsOocytesPolar BodiesSpindle ApparatusActinsanillinCaenorhabditis elegans ProteinsCasein Kinase IContractile ProteinsMyosins

Identifiers

PMID28701347
PMCPMC5576904
OpenAlexW2735739331

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.