Evidence map›Paper›PMID 28701341›Full record

ArticleMolecular biology of the cell2017

Computer simulations reveal mechanisms that organize nuclear dynein forces to separate centrosomes.

Alessandro De Simone, Pierre Gönczy

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Moonlighting at the Poles: Non-Canonical Functions of Centrosomes.Frontiers in cell and developmental biology · 2022
    Review
  4. Going with the flow: insights fromPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alessandro De SimoneSwiss Institute for Experimental Cancer Research, School of Life Sciences, Swiss Federal Institute of Technology, 1015 Lausanne, Switzerland.
Pierre GönczySwiss Institute for Experimental Cancer Research, School of Life Sciences, Swiss Federal Institute of Technology, 1015 Lausanne, Switzerland Pierre.Gonczy@epfl.ch.
École Polytechnique Fédérale de Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Centrosome separation along the surface of the nucleus at the onset of mitosis is critical for bipolar spindle assembly. Dynein anchored on the nuclear envelope is known to be important for centrosome separation, but it is unclear how nuclear dynein forces are organized in an anisotropic manner to promote the movement of centrosomes away from each other. Here we use computational simulations of

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell CycleCell NucleusCentrosomeComputer SimulationDyneinsMicrotubulesMitosisNuclear EnvelopeSpindle ApparatusCaenorhabditis elegans ProteinsDyneins

Identifiers

PMID28701341
PMCPMC5687019
OpenAlexW2734550183

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.