Evidence map›Paper›PMID 28701328›Full record

ArticleCirculation. Heart failure2017

Inpatient Mortality Risk Scores and Postdischarge Events in Hospitalized Heart Failure Patients: A Community-Based Study.

Sithu Win, Imad Hussain, Virginia B Hebl, Shannon M Dunlay, Margaret M Redfield

Abstract readMulticenter Study
In one paragraph

Article in Circulation. Heart failure, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Prognostic Models in Heart Failure: Hope or Hype?Journal of personalized medicine · 2025
    Review
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  5. Article
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  12. "Get with the Guidelines Heart Failure Risk Score" for mortality prediction in patients undergoing MitraClip.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sithu WinFrom the Department of Cardiovascular Disease, Division of Circulatory Failure, Mayo Clinic, Rochester, MN. Current address for Dr Hussain: Department of Medicine, Division of Cardiology, Houston Methodist Hospital, Houston, TX. Current address for Dr Hebl: Department of Medicine, Division of Cardiovascular Disease, Oregon Health & Science University, Portland, OR.
Imad HussainFrom the Department of Cardiovascular Disease, Division of Circulatory Failure, Mayo Clinic, Rochester, MN. Current address for Dr Hussain: Department of Medicine, Division of Cardiology, Houston Methodist Hospital, Houston, TX. Current address for Dr Hebl: Department of Medicine, Division of Cardiovascular Disease, Oregon Health & Science University, Portland, OR.
Virginia B HeblFrom the Department of Cardiovascular Disease, Division of Circulatory Failure, Mayo Clinic, Rochester, MN. Current address for Dr Hussain: Department of Medicine, Division of Cardiology, Houston Methodist Hospital, Houston, TX. Current address for Dr Hebl: Department of Medicine, Division of Cardiovascular Disease, Oregon Health & Science University, Portland, OR.
Shannon M DunlayFrom the Department of Cardiovascular Disease, Division of Circulatory Failure, Mayo Clinic, Rochester, MN. Current address for Dr Hussain: Department of Medicine, Division of Cardiology, Houston Methodist Hospital, Houston, TX. Current address for Dr Hebl: Department of Medicine, Division of Cardiovascular Disease, Oregon Health & Science University, Portland, OR.
Margaret M RedfieldFrom the Department of Cardiovascular Disease, Division of Circulatory Failure, Mayo Clinic, Rochester, MN. Current address for Dr Hussain: Department of Medicine, Division of Cardiology, Houston Methodist Hospital, Houston, TX. Current address for Dr Hebl: Department of Medicine, Division of Cardiovascular Disease, Oregon Health & Science University, Portland, OR. redfield.margaret@mayo.edu.

Funding

Recruitment and Phenotyping CoreP01HL076611 · NHLBI · MAYO CLINIC ROCHESTER · PI BURNETT, JOHN C · 2005 to 2015
$19.6M
CARDIOVASOLOGYT32HL007111 · NHLBI · MAYO CLINIC ROCHESTER · PI Barry A. Borlaug · 1985 to 2026
$8.7M
Mayo Heart Failure Regional Clinical CenterU10HL110262 · NHLBI · MAYO CLINIC ROCHESTER · PI REDFIELD, MARGARET M · 2012 to 2018
$3.6M
Mayo Heart Failure Regional Clinical CenterU01HL084907 · NHLBI · MAYO CLINIC ROCHESTER · PI REDFIELD, MARGARET M · 2006 to 2011
$2.4M
Treatment of Diastolic Heart Failure via AAV-9 Mediated Gene TransferR01HL105418 · NHLBI · MAYO CLINIC ROCHESTER · PI REDFIELD, MARGARET M · 2012 to 2015
$1.5M
End of Life Preferences and Healthcare Resource Use in Heart Failure PatientsK23HL116643 · NHLBI · MAYO CLINIC ROCHESTER · PI DUNLAY, SHANNON MARIE · 2013 to 2017
$739k
NHLBI NIH HHS K23 HL116643NHLBI NIH HHS P01 HL076611NHLBI NIH HHS R01 HL105418NHLBI NIH HHS T32 HL007111NHLBI NIH HHS U01 HL084907NHLBI NIH HHS U10 HL110262
6 · The paper itself

Abstract

backgroundThe Acute Decompensated Heart Failure National Registry (ADHERE) and Get With The Guidelines (GWTG) registries have developed simple heart failure (HF) in-hospital mortality risk scores. We hypothesized that HF scores predictive of in-hospital mortality would perform as well for early postdischarge mortality risk stratification. METHODS AND

resultsIn this single-center, community-based, retrospective study of all consecutive primary HF hospitalizations (6203 hospitalizations in 3745 patients) from 2000 to 2013, the ADHERE and GWTG risk scores were calculated from admission data. There were 176 (3.0%) and 399 (6.7%), 869 (14.7%), and 1272 (21.5%) deaths in-hospital and at 30, 90, and 180 days postdischarge, respectively. The GWTG but not ADHERE risk score was well calibrated for in-hospital mortality. Both the ADHERE (C statistic 0.66 and 0.67, 0.64, and 0.64) and GWTG (C statistic 0.74 and 0.73, 0.71, and 0.70) HF risk scores were similarly predictive of in-hospital and 30-, 90-, and 180-day postdischarge mortality. The ADHERE risk score identified 10% and the GWTG risk score identified 20% of hospitalizations where 180-day postdischarge mortality was 50%, a prognostic bench mark for hospice referral. In contrast, hospitalizations characterized as lowest risk by the ADHERE (57% of hospitalizations; 180-day mortality 16.2%) or GWTG score (20% of hospitalizations; 180-day mortality 8.0%) had substantially lower mortality (odds ratios high versus low risk of 5-8 [ADHERE] and 11-18 [GWTG] across time points;

conclusionsThe simple ADHERE and GWTG scores stratify hospitalized HF patients for both inpatient and early postdischarge mortality risk, allowing comprehensive risk assessment on admission.

Indexed as

InpatientsRegistriesAgedAged, 80 and overFemaleFollow-Up StudiesHeart FailureHospital MortalityHumansMaleOregonPatient ReadmissionPrognosisRetrospective StudiesRisk AssessmentRisk Factorsheart failurehospitalizationhospital readmission follow-up studieshumanrisk assessment

Identifiers

PMID28701328
PMCPMC5637410

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.