Evidence map›Paper›PMID 28701323›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2017

Renal denervation attenuates hypertension but not salt sensitivity in ET

Bryan K Becker, Amanda C Feagans, Daian Chen, Malgorzata Kasztan, Chunhua Jin, Joshua S Speed, Jennifer S Pollock, David M Pollock

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Current perspective on circadian function of the kidney.American journal of physiology. Renal physiology · 2024
    Review
  4. Article
  5. Article
  6. Circadian Control of Sodium and Blood Pressure Regulation.American journal of hypertension · 2021
    Review
  7. Article
  8. Article
  9. Article
  10. Loss of circadian geneAmerican journal of physiology. Renal physiology · 2020
    Article
  11. Review
  12. Autonomic nerves and circadian control of renal function.Autonomic neuroscience : basic & clinical · 2019
    Review
  13. Article
  14. Article
  15. Diurnal pattern in skin NaAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Bryan K BeckerCardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Amanda C FeagansCardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Daian ChenCardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Malgorzata KasztanCardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Chunhua JinCardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Joshua S SpeedCardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Jennifer S PollockCardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
David M PollockCardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama davidpollock@uabmc.edu.
University of Alabama at Birmingham · US

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANANDA BASU · 2013 to 2026
$19.5M
MECHANISMS OF HYPERTENSION AND CARDIOVASCULAR DISEASEST32HL007457 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Martin E Young · 1985 to 2026
$8.6M
Endothelin - Mechanisms in Hypertension and ObesityK99HL127178 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SPEED, JOSHUA S · 2016 to 2017
$308k
NHLBI NIH HHS K99 HL127178NHLBI NIH HHS T32 HL007457NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

Hypertension is a prevalent pathology that increases risk for numerous cardiovascular diseases. Because the etiology of hypertension varies across patients, specific and effective therapeutic approaches are needed. The role of renal sympathetic nerves is established in numerous forms of hypertension, but their contribution to salt sensitivity and interaction with factors such as endothelin-1 are poorly understood. Rats deficient of functional ET

Indexed as

DenervationAnimalsBaroreflexBlood PressureHypertensionKidneyParasympathetic Nervous SystemRatsRats, TransgenicReceptor, Endothelin BSodium Chloride, DietarySympathetic Nervous SystemReceptor, Endothelin BSodium Chloride, Dietaryautonomicscircadianendothelin Bsympathetic nerves

Identifiers

PMID28701323
PMCPMC5668611
OpenAlexW2735354275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.