SynthesisJournal of ovarian research2017
Is the oocyte quality affected by endometriosis? A review of the literature.
Synthesis in Journal of ovarian research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
105 citing papers in PubMed, 4 syntheses or guidelines pooled it, 246 citations in OpenAlex.
- Does endometriosis inflict harm on embryos? A systematic review of embryo morphokinetics analysed by time lapse monitoring in women with endometriosis.Archives of gynecology and obstetrics · 2024Pooled it
- Laser vaporization compared with other surgical techniques in women with ovarian endometrioma: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2023Pooled it
- Molecular Drivers of Developmental Arrest in the Human Preimplantation Embryo: A Systematic Review and Critical Analysis Leading to Mapping Future Research.International journal of molecular sciences · 2021Pooled it
- The impact of endometrioma on in vitro fertilisation/intra-cytoplasmic injection IVF/ICSI reproductive outcomes: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2021Pooled it
- Role of suppression of endometriosis with progestins before IVF-ET: a non-inferiority randomized controlled trial.BMC pregnancy and childbirth · 2021Trial
- A novel approach to treating Endometriosis-Related Repeated IVF failures- insights from single case report.Reproductive biology and endocrinology : RB&E · 2026Article
- PGT-A Chromosomal Outcomes in Trophectoderm Biopsies from Women with Endometriosis: A Retrospective IVF Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Oocyte quality in endometriosis-associated infertility: a narrative analysis of mechanisms and therapeutic options.Molecular biology reports · 2026Review
- Influence of endometriosis on the outcomes of assisted reproductive technology in poor ovarian responders with previous implantation failures.Obstetrics & gynecology science · 2026Article
- Three-Dimensional Architecture of Ectopic Epithelium and Vasculature in Ovarian Endometriosis Revealed by Tissue-Clearing Imaging.Cell proliferation · 2026Article
- Endometriosis disrupts oocyte metabolism and cortical granule function, impairing fertilization.Reproductive biology and endocrinology : RB&E · 2026Article
- Effectiveness of BMMSC and Dienogest on IL-1β, IL-8 Expression and Lesion Area in Endometriosis Mice.JBRA assisted reproduction · 2026Article
- Decoding the Endometriosis-Associated Infertility Microenvironment: A Review of FTIR and Raman Spectroscopic Insights into Follicular Fluid.Current issues in molecular biology · 2026Review
- Female fertility preservation: 25 years of progress, expanding indications and future prospects.Human reproduction update · 2026Review
- Review
- Hidden Burden of Fallopian Tube Endometriosis: Prevalence and Associations with Pelvic Pathology.Journal of clinical medicine · 2026Article
- Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway.Molecular medicine reports · 2026Article
- Identifying key determinants of cumulative live birth in women with ovarian endometrioma undergoing ethanol sclerotherapy followed byFrontiers in cell and developmental biology · 2026Article
- The Prevalence of Histologically Confirmed Endometriosis in Salpingectomy Specimens for Hydrosalpinx and Subsequent Reproductive Outcomes.Obstetrics and gynecology international · 2026Article
- Impact of hysteroscopy on pregnancy outcomes in women with endometriosis-associated infertility undergoing their first frozen-thawed embryo transfer: a retrospective cohort study.Frontiers in medicine · 2026Article
45 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis is an estrogen-dependent chronic inflammatory condition that affects women in their reproductive period causing infertility and pelvic pain. The disease, especially at the ovarian site has been shown to have a detrimental impact on ovarian physiology. Indeed, sonographic and histologic data tend to support the idea that ovarian follicles of endometriosis patients are decreased in number and more atretic. Moreover, the local intrafollicular environment of patients affected is characterized by alterations of the granulosa cell compartment including reduced P450 aromatase expression and increased intracellular reactive oxygen species generation. However, no comprehensive evaluation of the literature addressing the effect of endometriosis on oocyte quality from both a clinical and a biological perspective has so far been conducted. Based on this systematic review of the literature, oocytes retrieved from women affected by endometriosis are more likely to fail in vitro maturation and to show altered morphology and lower cytoplasmic mitochondrial content compared to women with other causes of infertility. Results from meta-analyses addressing IVF outcomes in women affected would indicate that a reduction in the number of mature oocytes retrieved is associated with endometriosis while a reduction in fertilization rates is more likely to be associated with minimal/mild rather than with moderate/severe disease. However, evidence in this field is still far to be conclusive, especially with regards to the effects of different stages of the disease and to the impact of patients' previous medical/surgical treatment(s).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.