Evidence map›Paper›PMID 28701183›Full record

ArticleJournal of medical case reports2017

Ruxolitinib found to cause eyelash growth: a case report.

Julia Song, Alice Song, Trisa Palmares, Michael Song, Harold Song

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Julia SongSouthern California Eye Physicians & Surgeons, 800 S. Fairmount Ave., #207, Pasadena, CA, 91105, USA. jsongmd@drsongvision.com.ORCID http://orcid.org/0000-0003-4278-6286
Alice SongCenter for Oculofacial & Orbital Surgery, 3771 Katella Ave., #209, Los Alamitos, CA, 90720, USA.
Trisa PalmaresSouthern California Eye Physicians & Surgeons, 800 S. Fairmount Ave., #207, Pasadena, CA, 91105, USA.
Michael SongCenter for Oculofacial & Orbital Surgery, 3771 Katella Ave., #209, Los Alamitos, CA, 90720, USA.
Harold SongCenter for Oculofacial & Orbital Surgery, 3771 Katella Ave., #209, Los Alamitos, CA, 90720, USA.
Southern California Eye Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypereosinophilic syndrome is a hematologic disorder in which the eosinophils proliferate. Oral Janus kinase inhibitors are known to be effective treating hypereosinophilic syndrome. Janus kinase inhibitors have also demonstrated efficacy in alopecia. Madarosis is a condition in which the eyelashes are missing or absent and can been seen in alopecia patients. CASE PRESENTATION: We present the case of a 77-year-old Asian man who was diagnosed with hypereosinophilic syndrome, refractive to all medications except ruxolitinib. He responded well. It was noted unexpectedly that his eyelashes grew much longer than they were normally.

conclusionsPrevious studies have demonstrated an improvement in alopecia areata, with increased hair growth on the head and eyebrows. This study demonstrates that longer eyelashes may be another effect of oral Janus kinase inhibitors. We report the first case of eyelash elongation and thickening in a patient taking ruxolitinib. Physicians and patients should be aware of the side effect of these Janus kinase inhibitors. Further investigation is needed to ascertain whether ruxolitinib or other interleukin inhibitors can aid in the treatment of madarosis.

Indexed as

AgedDiagnosis, DifferentialEyelashesHumansHypereosinophilic SyndromeJanus Kinase InhibitorsMaleNitrilesPruritusPyrazolesPyrimidinesTreatment OutcomeJanus Kinase InhibitorsNitrilesPyrazolesPyrimidinesruxolitinibAlopeciaHypereosinophilic syndromeJAKJanus kinaseMadarosisRuxolitinib

Identifiers

PMID28701183
PMCPMC5508627
OpenAlexW2735689974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.