Evidence map›Paper›PMID 28701166›Full record

ArticleRespiratory research2017

Which early life events or current environmental and lifestyle factors influence lung function in adolescents? - results from the GINIplus & LISAplus studies.

Agnes Luzak, Elaine Fuertes, Claudia Flexeder, Marie Standl, Andrea von Berg, Dietrich Berdel, Sibylle Koletzko, Joachim Heinrich, Dennis Nowak, Holger Schulz

Open access · goldAbstract read
In one paragraph

Article in Respiratory research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Agnes LuzakHelmholtz Zentrum München - German Research Center for Environmental Health, Institute of Epidemiology I, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Elaine FuertesHelmholtz Zentrum München - German Research Center for Environmental Health, Institute of Epidemiology I, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Claudia FlexederHelmholtz Zentrum München - German Research Center for Environmental Health, Institute of Epidemiology I, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Marie StandlHelmholtz Zentrum München - German Research Center for Environmental Health, Institute of Epidemiology I, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Andrea von BergDepartment of Pediatrics, Research Institute, Marien-Hospital Wesel, Pastor-Janßen-Str. 8-38, 46483, Wesel, Germany.
Dietrich BerdelDepartment of Pediatrics, Research Institute, Marien-Hospital Wesel, Pastor-Janßen-Str. 8-38, 46483, Wesel, Germany.
Sibylle KoletzkoDr von Hauner Children's Hospital, Ludwig-Maximilians-University of Munich, Lindwurmstr. 4, 80337, Munich, Germany.
Joachim HeinrichHelmholtz Zentrum München - German Research Center for Environmental Health, Institute of Epidemiology I, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Dennis NowakComprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research, Max-Lebsche-Platz 31, 81377, Munich, Germany.
Holger SchulzHelmholtz Zentrum München - German Research Center for Environmental Health, Institute of Epidemiology I, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany. schulz@helmholtz-muenchen.de.
Helmholtz Zentrum München · DEMarien Hospital Wesel · DELMU Klinikum · DELudwig-Maximilians-Universität München · DEUniversitat Pompeu Fabra · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious factors may affect lung function at different stages in life. Since investigations that simultaneously consider several factors are rare, we examined the relative importance of early life, current environmental/lifestyle factors and allergic diseases on lung function in 15-year-olds.

methodsBest subset selection was performed for linear regression models to investigate associations between 21 diverse early life events and current factors with spirometric parameters (forced vital capacity, forced expiratory volume in 1 s and maximal mid-expiratory flow (FEF

resultsA higher peak weight velocity and early lung infections were the early life events prevalently associated with airflow limitation and FEF

conclusionsAlthough the explained variance was mainly captured by well-known factors included in lung function prediction equations, our findings indicate early life and current factors that should be considered in studies on lung health among adolescents.

Indexed as

Adolescent DevelopmentEnvironmentLife StyleAdolescentAge FactorsAsthmaBody Mass IndexChi-Square DistributionFemaleForced Expiratory VolumeGermanyHumansHypersensitivityInfantInfant, NewbornLinear ModelsTobacco Smoke PollutionVitamin DAdolescenceDeterminantsEpidemiologyLung functionSpirometry

Identifiers

PMID28701166
PMCPMC5508705
OpenAlexW2734344323

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.