Evidence map›Paper›PMID 28700911›Full record

ArticleBiophysical journal2017

Non-equilibrium Membrane Homeostasis in Expanding Cellular Domains.

P Rowghanian, O Campàs

Abstract read
In one paragraph

Article in Biophysical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P RowghanianDepartment of Mechanical Engineering and California NanoSystems Institute, University of California, Santa Barbara, Santa Barbara, California.
O CampàsDepartment of Mechanical Engineering and California NanoSystems Institute, University of California, Santa Barbara, Santa Barbara, California. Electronic address: campas@engineering.ucsb.edu.

Funding

Bridging the Gap Between Molecular and Mechanical Control of Cell MorphogenesisR01GM113241 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI CAMPAS, OTGER · 2014 to 2018
$1.7M
NIGMS NIH HHS R01 GM113241
6 · The paper itself

Abstract

Many cell behaviors involve cell-shape transformations that impose considerable changes in the cell's surface area, requiring a constant adaptation of the cell's plasma membrane area to prevent cell lysis. Here, we theoretically describe the interplay between the plasma membrane dynamics and a physically connected cell cortex or wall, accounting for spatial variations in membrane recycling and tension. In-plane membrane net flows result naturally from these dynamics and, in the presence of an expanding cell cortex or wall, regions of converging or diverging flow patterns emerge. These flow patterns can potentially explain the spatial localization/segregation of membrane proteins in processes such as cell polarization. We also identify the relevant parameters that control membrane homeostasis and derive the range of parameters for which homeostatic states exist.

Indexed as

Cell EnlargementAnimalsCell MembraneCell WallEndocytosisExocytosisHomeostasisModels, BiologicalSurface TensionYeasts

Identifiers

PMID28700911
PMCPMC5510913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.