ArticleBiophysical journal2017
Assessing the Collective Dynamics of Motile Cilia in Cultures of Human Airway Cells by Multiscale DDM.
Article in Biophysical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Quantitative analysis of mucociliary activity by computational high-speed video reflection microscopy.European biophysics journal : EBJ · 2026Article
- Machine Learning Analysis of Cilia-Driven Particle Transport Distinguishes Primary Ciliary Dyskinesia Cilia from Normal Cilia.bioRxiv : the preprint server for biology · 2025Article
- Dynamics and emergence of metachronal waves in the ciliary band of a metazoan larva.Science advances · 2025Article
- Cilia dynamics create a dynamic barrier to penetration of the periciliary layer in human airway epithelia.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Fallopian tube rheology regulates epithelial cell differentiation and function to enhance cilia formation and coordination.Nature communications · 2024Article
- A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma.Nature communications · 2024Article
- Mucociliary transport in cystic fibrosis.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Measuring Biophysical Properties of Cilia Motility from Mammalian Tissues via Quantitative Video Analysis Methods.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Methods and Measures for Investigating Microscale Motility.Integrative and comparative biology · 2023Review
- Assessing motile cilia coverage and beat frequency in mammalianRoyal Society open science · 2023Article
- Phase-resolved dynamic wavefront imaging of cilia metachronal waves.Quantitative imaging in medicine and surgery · 2023Article
- Optimization of Primary Human Bronchial Epithelial 3D Cell Culture with Donor-Matched Fibroblasts and Comparison of Two Different Culture Media.International journal of molecular sciences · 2023Article
- Crowding and confinement act in concert to slow DNA diffusion within cell-sized droplets.iScience · 2022Article
- Ciliary Videomicroscopy: A Long Beat from the European Respiratory Society Guidelines to the Recognition as a Confirmatory Test for Primary Ciliary Dyskinesia.Diagnostics (Basel, Switzerland) · 2021Review
- Oxygenation as a driving factor in epithelial differentiation at the air-liquid interface.Integrative biology : quantitative biosciences from nano to macro · 2021Article
- Quantifying Intracellular Particle Flows by DIC Object Tracking.Biophysical journal · 2021Article
- Leveraging 3D Model Systems to Understand Viral Interactions with the Respiratory Mucosa.Viruses · 2020Review
- Multi-scale spatial heterogeneity enhances particle clearance in airway ciliary arrays.Nature physics · 2020Article
- Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma.Cell reports · 2020Article
- Investigation on Ciliary Functionality of Different Airway Epithelial Cell Lines in Three-Dimensional Cell Culture.Tissue engineering. Part A · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The technique of differential dynamic microscopy is extended here, showing that it can provide a powerful and objective method of video analysis for optical microscopy videos of in vitro samples of live human bronchial epithelial ciliated cells. These cells are multiciliated, with motile cilia that play key physiological roles. It is shown that the ciliary beat frequency can be recovered to match conventional analysis, but in a fully automated fashion. Furthermore, it is shown that the properties of spatial and temporal coherence of cilia beat can be recovered and distinguished, and that if a collective traveling wave (the metachronal wave) is present, this has a distinct signature and its wavelength and direction can be measured.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.