ArticlePloS one2017
Highly diverse and antimicrobial susceptible Escherichia coli display a naïve bacterial population in fruit bats from the Republic of Congo.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 39 citations in OpenAlex.
- Characterisation of Typical Enteropathogenic Escherichia coli (tEPEC) and bfpA Genes From Five Bat Species Reveals Australian Pteropus Spp. Are Natural tEPEC Hosts.MicrobiologyOpen · 2026Article
- Characterization of spontaneous gross and histologic findings in free-ranging Egyptian rousettes (Rousettus aegyptiacus) from Uganda with a review of reported pathogens.Veterinary research · 2026Article
- Prevalence and risk factors of antimicrobial resistance inOne health (Amsterdam, Netherlands) · 2026Article
- Clinical, Molecular, and Zoonotic Perspectives on Human Cases of Cryptosporidium sp. OTUi.Emerging infectious diseases · 2026Article
- Prevalence and patterns of antimicrobial resistance among wildlife populations in Africa: a systematic review.npj antimicrobials and resistance · 2026Article
- Environmental factors driving antimicrobial resistance in Indian flying foxes (Pteropus medius): one health implications.Scientific reports · 2025Article
- Adhesin genes expression among carbapenem-resistant uropathogenic Escherichia coli exposed to linalool and metformin.Molecular biology reports · 2025Article
- Characterization of Ravn virus viral shedding dynamics in experimentally infected Egyptian rousette bats (Journal of virology · 2025Article
- Ecological and public health dimensions of ESBL-producingVeterinary world · 2025Review
- Bats as an Important Source of Antimicrobial-Resistant Bacteria: A Systematic Review.Antibiotics (Basel, Switzerland) · 2024Review
- Comparative Genetic Characterization of CTX-M-ProducingMicroorganisms · 2023Article
- Dominance ofMicrobial genomics · 2023Article
- Identification of genes influencing the evolution ofMicrobial genomics · 2023Article
- Trends in Bacterial Pathogens of Bats: Global Distribution and Knowledge Gaps.Transboundary and emerging diseases · 2023Review
- Evidence of Antimicrobial Resistance in Bats and Its Planetary Health Impact for Surveillance of Zoonotic Spillover Events: A Scoping Review.International journal of environmental research and public health · 2022Article
- Longitudinal Study on Extended-Spectrum Beta-Lactamase-Microorganisms · 2022Article
- Close genetic linkage between human and companion animal extraintestinal pathogenicCurrent research in microbial sciences · 2022Article
- Presence of β-Lactamase-producing Enterobacterales andInternational journal of molecular sciences · 2021Article
- The Kidney-Associated Microbiome of Wild-CaughtAnimals : an open access journal from MDPI · 2021Article
- Characterization of beta-lactam-resistantMicrobial genomics · 2021Article
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Authors and funding
11 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bats are suspected to be a reservoir of several bacterial and viral pathogens relevant to animal and human health, but studies on Escherichia coli in these animals are sparse. We investigated the presence of E. coli in tissue samples (liver, lung and intestines) collected from 50 fruit bats of five different species (Eidolon helvum, Epomops franqueti, Hypsignathus monstrosus, Myonycteris torquata, Rousettus aegyptiacus) of two different areas in the Republic of Congo between 2009 and 2010. To assess E. coli pathotypes and phylogenetic relationships, we determined the presence of 59 virulence associated genes and multilocus sequence types (STs). Isolates were further tested for their susceptibility to several antimicrobial substances by agar disk diffusion test and for the presence of an Extended-Spectrum Beta-Lactamase phenotype. E. coli was detected in 60% of the bats analysed. The diversity of E. coli strains was very high, with 37 different STs within 40 isolates. Occasionally, we detected sequence types (e.g. ST69, ST127, and ST131) and pathotypes (e.g. ExPEC, EPEC and atypical EPEC), which are known pathogens in human and/or animal infections. Although the majority of strains were assigned to phylogenetic group B2 (46.2%), which is linked with the ExPEC pathovar, occurrence of virulence-associated genes in these strains were unexpectedly low. Due to this, and as only few of the E. coli isolates showed intermediate resistance to certain antimicrobial substances, we assume a rather naïve E. coli population, lacking contact to humans or domestic animals. Future studies featuring in depth comparative whole genome sequence analyses will provide insights into the microevolution of this interesting strain collection.
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