ArticlePLoS medicine2017
Time for trauma immunology.
Article in PLoS medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Hallmarks of the multidimensional immune response to trauma in humans.Nature immunology · 2026Review
- Novel insights into diagnosis and management of hyperreactivity: a narrative review.Journal of thoracic disease · 2025Review
- A China-Based exploration of surgical timing for polytrauma with a focus on fracture reconstruction.World journal of emergency surgery : WJES · 2025Article
- Effect on Syndecan-1 and Hyaluronan Levels Depending on Multiple Organ Failure, Coagulopathy and Survival: An Observational Study in Major Trauma Patients.Journal of clinical medicine · 2024Article
- Shared and unique patterns of autonomous human endogenous retrovirus loci transcriptomes in CD14 + monocytes from individuals with physical trauma or infection with COVID-19.Retrovirology · 2024Article
- Severe traumatic injury is associated with profound changes in DNA methylation.NPJ genomic medicine · 2024Article
- The Ambivalent Role of miRNA-21 in Trauma and Acute Organ Injury.International journal of molecular sciences · 2024Review
- Breaking barriers in trauma research: A narrative review of opportunities to leverage veterinary trauma for accelerated translation to clinical solutions for pets and people.Journal of clinical and translational science · 2024Review
- Glomerular injury after trauma, burn, and sepsis.Journal of nephrology · 2023Review
- Towards systems immunology of critical illness at scale: from single cell 'omics to digital twins.Trends in immunology · 2023Review
- Importance of the neutrophil‑to‑lymphocyte ratio as a prognostic factor in patients with spleen trauma: A single center experience.Biomedical reports · 2022Article
- Inferring Tissue-Specific, TLR4-Dependent Type 17 Immune Interactions in Experimental Trauma/Hemorrhagic Shock and Resuscitation Using Computational Modeling.Frontiers in immunology · 2022Article
- The Use of Multiplexing to Identify Cytokine and Chemokine Networks in the Immune-Inflammatory Response to Trauma.Antioxidants & redox signaling · 2021Review
- Trauma-induced coagulopathy: The past, present, and future.Journal of thrombosis and haemostasis : JTH · 2019Review
- Computational evidence for an early, amplified systemic inflammation program in polytrauma patients with severe extremity injuries.PloS one · 2019Article
- The innate immune response to ischemic injury: a multiscale modeling perspective.BMC systems biology · 2018Article
- Innate immune responses to trauma.Nature immunology · 2018Review
- Systemic immune response of burns from the acute to chronic phase.Acute medicine & surgeryReview
- From trauma to chronicity: Understanding the incidence and early immune changes of chronic complications in polytrauma patients.Science progressObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Timothy Billiar summarizes the role of the innate immune response in the clinical course following severe injury and envisions a field of "trauma immunology."
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.