ArticleeLife2017
Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance.
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Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
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Who cites it
39 citing papers in PubMed, 57 citations in OpenAlex.
- Bmp9 regulates Notch signaling and the temporal dynamics of angiogenesis via Lunatic Fringe.Developmental cell · 2026Article
- Computationally resolved neuroprogenitor cell biomarkers associate with human disorders.Stem cell reports · 2025Article
- The Notch pathway: A guardian of cell fate during neurogenesis.Current opinion in cell biology · 2025Review
- Unique transcriptomic responses of rat and human alveolar macrophages in an in vitro model of overload with TiOParticle and fibre toxicology · 2025Article
- The Hippo pathway and p27Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Rational design of a Lfng-enhancer AAV construct drives specific and efficient gene expression in inner ear supporting cells.Hearing research · 2025Article
- Lfng-expressing centroacinar cell is a unique cell-of-origin for p53 deficient pancreatic cancer.Oncogene · 2025Article
- Red Blood Cell-Related Phenotype-Genotype Correlations in Chronic and Acute Critical Illnesses (Traumatic Brain Injury Cohort and COVID-19 Cohort).International journal of molecular sciences · 2025Article
- Reprogramming withPNAS nexus · 2024Article
- Jagged-1+ skin Tregs modulate cutaneous wound healing.Scientific reports · 2024Article
- Article
- SoxC transcription factors shape the epigenetic landscape to establish competence for sensory differentiation in the mammalian organ of Corti.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- DNA methylation in the mouse cochlea promotes maturation of supporting cells and contributes to the failure of hair cell regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Notch signaling as a master regulator of adult neurogenesis.Frontiers in neuroscience · 2023Review
- Review
- Augmenting neurogenesis rescues memory impairments in Alzheimer's disease by restoring the memory-storing neurons.The Journal of experimental medicine · 2022Article
- Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Lunatic Fringe-GFP Marks Lamina-Specific Astrocytes That Regulate Sensory Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Article
- Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration.Developmental cell · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Fatih SemerciProgram in Developmental Biology, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-0512-1827
William Tin-Shing ChoiProgram in Developmental Biology, Baylor College of Medicine, Houston, United States.
Aleksandar BajicJan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, United States.
Aarohi ThakkarJan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, United States.
Juan Manuel EncinasJan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, United States.
Frederic DepreuxDepartment of Cell Biology and Anatomy, Rosalind Franklin University of Medicine and Science, Chicago, United States.
Neil SegilDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, United States.
Andrew K GrovesProgram in Developmental Biology, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-0784-7998
Mirjana Maletic-SavaticProgram in Developmental Biology, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-6548-4662
Baylor College of Medicine · USIkerbasque · ESRosalind Franklin University of Medicine and Science · USUniversity of Southern California · US
Funding
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9MVirology CoreP30AI036211 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BUTEL, JANET S · 1994 to 2015
$21.7MSteps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, NEUL, JEFFREY L · 2014 to 2019
$7.8MEnhancing Atoh1 function in hair cell regenerationR01DC014832 · NIDCD · WASHINGTON UNIVERSITY · PI Gabriel Corfas, Andrew K Groves · 2016 to 2026
$6.7MTraining in Hearing & Communication NeuroscienceT32DC009975 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christopher A Shera · 2009 to 2026
$5.0MGenetic Regulation of Cochlear DevelopmentR01DC006185 · NIDCD · HOUSE RESEARCH INSTITUTE · PI GROVES, ANDREW K · 2003 to 2014
$3.6MCELL CYCLE IN DEVELOPMENT / REGENERATION OF THE INNER EAR01DC004189 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SEGIL, NEIL · 1999 to 2011
$3.6MImaging Mass Spectrometry for metabolome mappingR01GM120033 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI LIU, ZHANDONG, MALETIC-SAVATIC, MIRJANA · 2017 to 2021
$2.5MBD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430kTecan EVO GenePaint robotS10OD016167 · OD · BAYLOR COLLEGE OF MEDICINE · PI LJUNGBERG, CECILIA · 2013 to 2013
$215kNCI NIH HHS P30 CA125123NCRR NIH HHS S10 RR024574NIAID NIH HHS P30 AI036211NICHD NIH HHS U54 HD083092NIDCD NIH HHS R01 DC004189NIDCD NIH HHS R01 DC006185NIDCD NIH HHS R01 DC014832NIDCD NIH HHS T32 DC009975NIGMS NIH HHS R01 GM120033NIH HHS S10 OD016167
Abstract
Hippocampal neural stem cells (NSCs) integrate inputs from multiple sources to balance quiescence and activation. Notch signaling plays a key role during this process. Here, we report that Lunatic fringe (
Indexed as
Signal TransductionAnimalsCell CycleCell ProliferationGene Expression RegulationGlycosyltransferasesHippocampusMiceNeural Stem CellsReceptors, NotchGlycosyltransferasesLfng protein, mouseReceptors, Notchadult hippocampal neurogenesisdevelopmental biologyLineage tracingLunatic fringemousemouse modelsneural stem cellsNotch signalingstem cells
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.