Evidence map›Paper›PMID 28699546›Full record

ArticleBMC medical informatics and decision making2017

An active learning-enabled annotation system for clinical named entity recognition.

Yukun Chen, Thomas A Lask, Qiaozhu Mei, Qingxia Chen, Sungrim Moon, Jingqi Wang, Ky Nguyen, Tolulola Dawodu, Trevor Cohen, Joshua C Denny and 1 more

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Clinical concept extraction: A methodology review.Journal of biomedical informatics · 2020
    Review
  9. Cost-aware active learning for named entity recognition in clinical text.Journal of the American Medical Informatics Association : JAMIA · 2019
    Article
  10. Cost-sensitive Active Learning for Phenotyping of Electronic Health Records.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yukun ChenPieces Technologies Inc, Dallas, TX, USA.
Thomas A LaskDepartment of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.
Qiaozhu MeiSchool of Information, University of Michigan, Ann Arbor, MI, USA.
Qingxia ChenDepartment of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.
Sungrim MoonDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Jingqi WangSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Ky NguyenSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Tolulola DawoduSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Trevor CohenSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Joshua C DennyDepartment of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.
Hua XuSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA. hua.xu@uth.tmc.edu.

Funding

Real-time Disambiguation of Abbreviations in Clinical NotesR01LM010681 · NLM · VANDERBILT UNIVERSITY · PI XU, HUA · 2010 to 2017
$3.1M
NLM NIH HHS R01 LM010681
6 · The paper itself

Abstract

backgroundActive learning (AL) has shown the promising potential to minimize the annotation cost while maximizing the performance in building statistical natural language processing (NLP) models. However, very few studies have investigated AL in a real-life setting in medical domain.

methodsIn this study, we developed the first AL-enabled annotation system for clinical named entity recognition (NER) with a novel AL algorithm. Besides the simulation study to evaluate the novel AL algorithm, we further conducted user studies with two nurses using this system to assess the performance of AL in real world annotation processes for building clinical NER models.

resultsThe simulation results show that the novel AL algorithm outperformed traditional AL algorithm and random sampling. However, the user study tells a different story that AL methods did not always perform better than random sampling for different users.

conclusionsWe found that the increased information content of actively selected sentences is strongly offset by the increased time required to annotate them. Moreover, the annotation time was not considered in the querying algorithms. Our future work includes developing better AL algorithms with the estimation of annotation time and evaluating the system with larger number of users.

Indexed as

Medical InformaticsNatural Language ProcessingProblem-Based LearningComputer SimulationHumans

Identifiers

PMID28699546
PMCPMC5506567

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.