Trial reportNeurogastroenterology and motility2017
The pharyngeal contractile integral is a useful indicator of pharyngeal swallowing impairment.
Trial report in Neurogastroenterology and motility, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Does Medialization Improve Swallowing Function in Patients with Unilateral Vocal Fold Paralysis? A Systematic Review.Dysphagia · 2022Pooled it
- Pooled it
- Evaluation of post-laryngectomy dysphagia rehabilitation using High-Resolution impedance manometry: an exploratory study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Trial
- Effects of Aging on Correlation of Striated Esophageal and Pharyngeal Deglutitive Motor Function.Gastroenterology research and practice · 2026Article
- Characterization of pharyngeal contractile integral using pharyngeal manometry in children.Journal of pediatric gastroenterology and nutrition · 2024Article
- A Case of a Patient With Spinal Muscular Atrophy With Dysphagia Who Acquired Vacuum Swallowing.Cureus · 2024Article
- Potential for Behavioural Pressure Modulation at the Upper Oesophageal Sphincter in Healthy Swallowing.Dysphagia · 2022Article
- Structural Validity, Internal Consistency, and Rater Reliability of the Modified Barium Swallow Impairment Profile: Breaking Ground on a 52,726-Patient, Clinical Data Set.Journal of speech, language, and hearing research : JSLHR · 2022Article
- Videofluoroscopic and manometric outcomes of cricopharyngeus balloon dilation for treatment of pharyngo-esophageal dysphagia associated with nasopharyngeal cancer: A case series.Laryngoscope investigative otolaryngology · 2021Article
- Effect of Capsaicinoids on Neurophysiological, Biochemical, and Mechanical Parameters of Swallowing Function.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021Article
- Incoordination during the pharyngeal phase in severe dysphagia due to lateral medullary syndrome.Clinical case reports · 2021Article
- Article
- Impact of Sensory Stimulation on Pharyngo-esophageal Swallowing Biomechanics in Adults with Dysphagia: A High-Resolution Manometry Study.Dysphagia · 2020Article
- Pressure abnormalities in patients with Zenker's diverticulum using pharyngeal high-resolution manometry.Laryngoscope investigative otolaryngology · 2020Article
- Best Practices in Modified Barium Swallow Studies.American journal of speech-language pathology · 2020Review
- Review
- Pharyngeal contractile and regulatory characteristics are distinct during nutritive oral stimulus in preterm-born infants: Implications for clinical and research applications.Neurogastroenterology and motility · 2019Article
- Systematic Review of Pharyngeal and Esophageal Manometry in Healthy or Dysphagic Older Persons (>60 years).Geriatrics (Basel, Switzerland) · 2018Review
- Defining pharyngeal contractile integral during high-resolution manometry in neonates: a neuromotor marker of pharyngeal vigor.Pediatric research · 2018Article
- The Usefulness of Swallowing Pressure Assessment in the Identification of Mild Pharyngeal Weakness of Myasthenia Gravis: A Case Report.Case reports in neurologyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundA limitation to the expanded use of high-resolution pharyngeal manometry (HRPM) in clinical practice is the lack of useful pharyngeal parameters that are easy to interpret, generalizable between patients, and do not require specialized software. In this study, we sought to test the relationship between the pharyngeal contractile integral (PhCI) with videofluoroscopic abnormalities as assessed with the Modified Barium Swallow Impairment Profile
methodsAdult dysphagic patients were recruited to undergo simultaneous HRPM and videofluoroscopy during a standardized swallowing protocol. KEY
resultsThirty-six patients were included in the study. The mean PhCI was 247 mm Hg·cm·s (range 2-488 mm Hg·cm·s). The lower pharyngeal total (PT) group (N=20; mean PT=3.9) had a mean PhCI of 299 mm Hg·cm·s, while the higher PT group (N=16; mean PT=12.7) had a mean PhCI score of 188 mm Hg·cm·s (P=.01). There was also a significant negative correlation between normalized PhCI to PT scores (r=-.47; P=.004). Patients with higher PhCIs exhibited less severe penetration-aspiration scores on thin liquids (1.44 vs 3.78; P=.03) and all consistencies combined (1.21 vs 1.99; P=.03). CONCLUSIONS & INFERENCES: The PhCI is a useful indicator of the presence of pharyngeal swallowing impairment and is technically simple to calculate with currently available software programs. Advancement of software is necessary to refine the clinical value of this parameter. High-resolution pharyngeal manometry has the potential to be a valuable adjunct procedure for the evaluation and treatment of dysphagic individuals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.