Evidence map›Paper›PMID 28699060›Full record

ReviewJournal of general internal medicine2017

Assessing the Burden of Treatment.

Gabriela Spencer-Bonilla, Ana R Quiñones, Victor M Montori, International Minimally Disruptive Medicine Workgroup

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of general internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05593835 (Protocol for a Cluster Randomised Trial of a Goal-Oriented Care Approach for Multimorbidity Patients Supported by a Digital Platform), which is not on this map. Cited by 69 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05593835 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Protocol for a Cluster Randomised Trial of a Goal-Oriented Care Approach for Multimorbidity Patients Supported by a Digital Platform

TypeinterventionalSponsorUniversidade Nova de LisboaRan2025 to 2027Enrolled1,380ConditionsChronic DiseaseArmsMETHIS Platform, Goal-Oriented Care Training Program
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Everyday Lives of Middle-Aged Persons with Multimorbidity: A Mixed Methods Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Comorbidities and depressive symptoms among older adults with asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022
    Trial
  8. Trial
  9. Price Transparency and Patient Empowerment.Health care analysis : HCA : journal of health philosophy and policy · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Treatment Burden Among Older Adults in the United States, 2022.Journal of the American Geriatrics Society · 2025
    Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gabriela Spencer-BonillaKnowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA.
Ana R QuiñonesSchool of Public Health, Oregon Health & Science University, Portland, OR, 97239, USA.
Victor M MontoriKnowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA. montori.victor@mayo.edu.
International Minimally Disruptive Medicine Workgroup

Funding

Mayo Clinic Center for Translational Science ActivitiesKL2TR000136 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$6.6M
NCATS NIH HHS KL2 TR000136
6 · The paper itself

Abstract

Current healthcare systems and guidelines are not designed to adapt to care for the large and growing number of patients with complex care needs and those with multimorbidity. Minimally disruptive medicine (MDM) is an approach to providing care for complex patients that advances patients' goals in health and life while minimizing the burden of treatment. Measures of treatment burden assess the impact of healthcare workload on patient function and well-being. At least two of these measures are now available for use with patients living with chronic conditions. Here, we describe these measures and how they can be useful for clinicians, researchers, managers, and policymakers. Their work to improve the care of high-cost, high-use, complex patients using innovative patient-centered models such as MDM should be supported by periodic large-scale assessments of treatment burden.

Indexed as

Cost of IllnessHumansPatient-Centered CareTreatment Outcomechronic diseaseminimally disruptive medicinemultimorbidityquality measurestreatment burden

Identifiers

PMID28699060
PMCPMC5602768

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.