Evidence map›Paper›PMID 28698967›Full record

ArticleMolecular neurobiology2018

Endogenous Expression of ODN-Related Peptides in Astrocytes Contributes to Cell Protection Against Oxidative Stress: Astrocyte-Neuron Crosstalk Relevance for Neuronal Survival.

Ikram Ghouili, Seyma Bahdoudi, Fabrice Morin, Fatma Amri, Yosra Hamdi, Pierre Michael Coly, Marie-Laure Walet-Balieu, Jérôme Leprince, Sami Zekri, Hubert Vaudry and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

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  5. Astrocytes: GABAceptive and GABAergic Cells in the Brain.Frontiers in cellular neuroscience · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Ikram GhouiliUniversité de Tunis El Manar, Faculté des Sciences de Tunis, Research Unit UR/11ES09, Laboratory of Functional Neurophysiology and Pathology, 2092, Tunis, Tunisia.
Seyma BahdoudiUniversité de Tunis El Manar, Faculté des Sciences de Tunis, Research Unit UR/11ES09, Laboratory of Functional Neurophysiology and Pathology, 2092, Tunis, Tunisia.
Fabrice MorinInserm U1239, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandie, 76128, Mont-Saint-Aignan, France.
Fatma AmriUniversité de Tunis El Manar, Faculté des Sciences de Tunis, Research Unit UR/11ES09, Laboratory of Functional Neurophysiology and Pathology, 2092, Tunis, Tunisia.
Yosra HamdiUniversité de Tunis El Manar, Faculté des Sciences de Tunis, Research Unit UR/11ES09, Laboratory of Functional Neurophysiology and Pathology, 2092, Tunis, Tunisia.
Pierre Michael ColyInserm U1239, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandie, 76128, Mont-Saint-Aignan, France.
Marie-Laure Walet-BalieuRegional Proteomic Platform (Pissaro), IRIB, University of Rouen Normandie, Mont-Saint-Aignan, France.
Jérôme LeprinceInserm U1239, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandie, 76128, Mont-Saint-Aignan, France.
Sami ZekriElectron Microscopy Laboratory, Faculty of Medicine of Tunis, University Tunis El Manar, Tunis, Tunisia.
Hubert VaudryRegional Platform for Cell Imaging of Normandie (PRIMACEN), IRIB, University of Rouen Normandie, Mont-Saint-Aignan, France.
David VaudryInserm U1239, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandie, 76128, Mont-Saint-Aignan, France.
Hélène CastelInserm U1239, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandie, 76128, Mont-Saint-Aignan, France.
Mohamed AmriUniversité de Tunis El Manar, Faculté des Sciences de Tunis, Research Unit UR/11ES09, Laboratory of Functional Neurophysiology and Pathology, 2092, Tunis, Tunisia.
Marie-Christine TononInserm U1239, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandie, 76128, Mont-Saint-Aignan, France. marie-christine.tonon@univ-rouen.fr.
Olfa Masmoudi-KoukiUniversité de Tunis El Manar, Faculté des Sciences de Tunis, Research Unit UR/11ES09, Laboratory of Functional Neurophysiology and Pathology, 2092, Tunis, Tunisia. olfa.masmoudi@fst.utm.tn.ORCID http://orcid.org/0000-0001-8062-6561
Tunis University · TNInserm · FRNormandie Université · FRUniversité de Rouen Normandie · FR

Funding

France-Tunisia exchange program CMCU-Campus France/PHC Utique grant number 16G0820/34940PKInserm (U1239), the Institute for Medical Research and Innovation (IRIB) U1239Laboratory of Functional Neurophysiology and Pathology UR/11ES09
6 · The paper itself

Abstract

Astroglial cells are important actors in the defense of brain against oxidative stress injuries. Glial cells synthesize and release the octadecaneuropeptide ODN, a diazepam-binding inhibitor (DBI)-related peptide, which acts through its metabotropic receptor to protect neurons and astrocytes from oxidative stress-induced apoptosis. The purpose of the present study is to examine the contribution of the endogenous ODN in the protection of astrocytes and neurons from moderate oxidative stress. The administration of H

Indexed as

NeuroprotectionOxidative StressAnimalsAstrocytesCatalaseCells, CulturedCell SurvivalCulture Media, ConditionedDiazepam Binding InhibitorHydrogen PeroxideNeuronsNeuropeptidesNeuroprotective AgentsPeptide FragmentsRats, WistarRNA, MessengerCatalaseCulture Media, ConditionedDiazepam Binding Inhibitordiazepam binding inhibitor (33-50)Hydrogen PeroxideNeuropeptidesNeuroprotective AgentsPeptide FragmentsRNA, MessengerRNA, Small InterferingSuperoxide DismutaseCell deathGlio- and neuro-protectionGliopeptide ODNModerate oxidative stressReactive oxygen species

Identifiers

PMID28698967
OpenAlexW2734538379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.