Trial reportBioMed research international2017
The Role of Interleukin-17, Interleukin-23, and Transforming Growth Factor-
Trial report in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04520048 (Exploratory Study. Endothelial Function and Vascular-tropic Biomarkers), which is not on this map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exploratory Study. Endothelial Function and Vascular-tropic Biomarkers: Predictive Indicators of the Progression of Hypertensive Disorders in Pregnancy to Pre-eclampsia?
Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- γδ T cell frequencies are altered in HIV positive pregnant South African women and are associated with preterm birth.PloS one · 2020Trial
- Unveiling the Diagnostic and Prognostic Value of Inflammatory Cytokines in Preeclampsia: A Review of Ιnterleukins IL-15, IL-16, IL-17 and IL-35.Journal of clinical medicine · 2025Review
- The evaluation role of T helper 17 cells in pregnancy and abortion: A molecular and future perspective: Narrative review.International journal of reproductive biomedicine · 2025Review
- Understanding the role of immune-mediated inflammatory disease related cytokines interleukin 17 and 23 in pregnancy: A systematic review.Journal of translational autoimmunity · 2025Review
- Analyzing the relationship of RNA and DNA methylation with gene expression.Genome biology · 2025Article
- The role of the placenta-brain axis in psychoneuroimmune programming.Brain, behavior, & immunity - health · 2024Article
- Article
- Characterization of extracellular vesicles in COVID-19 infection during pregnancy.Frontiers in cell and developmental biology · 2023Article
- Chronic Venous Disease during Pregnancy Causes a Systematic Increase in Maternal and Fetal Proinflammatory Markers.International journal of molecular sciences · 2022Article
- IL-17A polymorphism (rs2275913) and levels are associated with preeclampsia pathogenesis in Chinese patients.BMC medical genomics · 2021Article
- Maternal Serum Cytokine Concentrations in Healthy Pregnancy and Preeclampsia.Journal of pregnancy · 2021Review
- Cytokine Patterns in Maternal Serum From First Trimester to Term and Beyond.Frontiers in immunology · 2021Article
- Interleukin-17 signaling mediates cytolytic natural killer cell activation in response to placental ischemia.American journal of physiology. Regulatory, integrative and comparative physiology · 2020Article
- The exploration of Hashimoto's Thyroiditis related miscarriage for better treatment modalities.International journal of medical sciences · 2020Review
- Seminal plasma and CD4Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020Article
- Regulatory B Cells Are Decreased and Impaired in Their Function in Peripheral Maternal Blood in Pre-term Birth.Frontiers in immunology · 2020Article
- Th17 Cells and IL-17 As Novel Immune Targets in Ovarian Cancer Therapy.Journal of oncology · 2020Article
- The Role of Highly Active Antiretroviral Therapy (HAART) on Interleukin 17A (IL-17A) in Normotensive and Preeclamptic Black South African Women.Infectious diseases in obstetrics and gynecology · 2020Article
- Nicotine protects fetus against LPS-induced fetal growth restriction through ameliorating placental inflammation and vascular development in late pregnancy in rats.Bioscience reports · 2019Article
- Effects of first-generation in utero exposure to diesel engine exhaust on second-generation placental function, fatty acid profiles and foetal metabolism in rabbits: preliminary results.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of the study was to evaluate the role of Interleukin-17 (IL-17), Interleukin-23 (IL-23), and transforming growth factor- MATERIAL AND
methodsThe study comprised 34 patients with pregnancy complicated by fetal growth restriction (FGR) associated with preeclampsia (PE), as well as 35 healthy pregnant women. The concentrations of IL-17, IL-23, and TGF-
resultsThere were higher concentrations of IL-17 in the study group when compared to the controls. In the group of patients with placental insufficiency, the levels of IL-17 positively correlated with systolic blood pressure (
conclusionsIt seems possible that the increased concentrations of IL-17 and the deficiency of TGF-
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.