Evidence map›Paper›PMID 28698560›Full record

ArticleScientific reports2017

All muscarinic acetylcholine receptors (M

Beatrice Mihaela Radu, Antonio Marco Maria Osculati, Eda Suku, Adela Banciu, Grygoriy Tsenov, Flavia Merigo, Marzia Di Chio, Daniel Dumitru Banciu, Cristina Tognoli, Petr Kacer and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 52 citations in OpenAlex.

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  13. Polyethylenimine-Poly(lactic-ACS central science · 2021
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  17. Precapillary sphincters and pericytes at first-order capillaries as key regulators for brain capillary perfusion.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Beatrice Mihaela RaduDepartment of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, 37134, Italy.ORCID 0000-0003-4421-2163
Antonio Marco Maria OsculatiDepartment of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, 27100, Italy.
Eda SukuDepartment of Biotechnology, University of Verona, Verona, 37134, Italy.
Adela BanciuDepartment of Anatomy, Animal Physiology and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, 050095, Romania.
Grygoriy TsenovDepartment of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, 37134, Italy.
Flavia MerigoDepartment of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, 37134, Italy.
Marzia Di ChioDepartment of Public Health and Community Medicine, University of Verona, Verona, 37134, Italy.
Daniel Dumitru BanciuDepartment of Anatomy, Animal Physiology and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, 050095, Romania.
Cristina TognoliDepartment of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, 37134, Italy.
Petr KacerNational Institute of Mental Health, Klecany, 25067, Czech Republic.
Alejandro GiorgettiDepartment of Biotechnology, University of Verona, Verona, 37134, Italy.
Mihai RaduDepartment of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, 37134, Italy. mihai.radu@univr.it.ORCID 0000-0003-1128-8153
Giuseppe BertiniDepartment of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, 37134, Italy.ORCID 0000-0002-6031-5130
Paolo Francesco FabeneDepartment of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, 37134, Italy.
University of Verona · ITUniversity of Bucharest · RONational Institute of Mental Health · CZUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical and experimental studies indicate that muscarinic acetylcholine receptors are potential pharmacological targets for the treatment of neurological diseases. Although these receptors have been described in human, bovine and rat cerebral microvascular tissue, a subtype functional characterization in mouse brain endothelium is lacking. Here, we show that all muscarinic acetylcholine receptors (M

Indexed as

AcetylcholineAllosteric SiteAnimalsBinding SitesBrainCalcium SignalingEndothelial CellsEndothelium, VascularMice, Inbred BALB CMicrovesselsReceptors, MuscarinicReceptors, NicotinicAcetylcholineReceptors, MuscarinicReceptors, Nicotinic

Identifiers

PMID28698560
PMCPMC5506046
OpenAlexW2731904776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.