Evidence map›Paper›PMID 28698299›Full record

ArticleGenes & development2017

Stephano S Mello, Carolyn Sinow, Nitin Raj, Pawel K Mazur, Kathryn Bieging-Rolett, Daniela Kenzelmann Broz, Jamie F Conklin Imam, Hannes Vogel, Laura D Wood, Julien Sage and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
148citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

148 citing papers in PubMed, 2 syntheses or guidelines pooled it, 204 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Rapid Exploratory Data Visualization for Cancer Genomics.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. The crosstalk of mTrends in biochemical sciences · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Computational and structural biotechnology journal · 2024
    Review
  19. Article
  20. Review

88 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Stephano S MelloDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA.
Carolyn SinowDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA.
Nitin RajDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA.
Pawel K MazurDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California 94305, USA.
Kathryn Bieging-RolettDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA.
Daniela Kenzelmann BrozDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA.
Jamie F Conklin ImamDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California 94305, USA.
Hannes VogelDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Laura D WoodDepartment of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.
Julien SageDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California 94305, USA.
Tetsuro HiroseInstitute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.
Shinichi NakagawaRNA Biology Laboratory, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
John RinnDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Laura D AttardiDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA.
Stanford University · USHokkaido University · JPCancer Research Center · USHarvard University · US

Funding

Integrative approaches to elucidate p53 transcriptional networks during carcinogenesisR35CA197591 · NCI · STANFORD UNIVERSITY · PI LAURA D ATTARDI · 2015 to 2026
$11.6M
Epigenetic Regulation by Large Non-Coding RNAs in the p53 Mediated DNA Damage ResR01ES020260 · NIEHS · HARVARD UNIVERSITY · PI RINN, JOHN LOUIS · 2011 to 2015
$2.1M
The SMYD3-ERK5 signaling module in pancreatic cancerR00CA197816 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MAZUR, PAWEL K. · 2017 to 2019
$732k
NCI NIH HHS R00 CA197816NCI NIH HHS R35 CA197591NIEHS NIH HHS R01 ES020260
6 · The paper itself

Abstract

The

Indexed as

AnimalsCarcinoma, Pancreatic DuctalCells, CulturedCell Transformation, NeoplasticDNA RepairFibroblastsGene Expression ProfilingGene Expression Regulation, NeoplasticHCT116 CellsHumansMiceRNA, Long NoncodingTumor Suppressor Protein p53NEAT1 long non-coding RNA, humanNEAT1 long non-coding RNA, mouseRNA, Long NoncodingTumor Suppressor Protein p53lincRNANeat1p53pancreatic cancertumor suppression

Identifiers

PMID28698299
PMCPMC5538433
OpenAlexW2734671954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.