Evidence map›Paper›PMID 28698275›Full record

ArticlemBio2017

CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for

Jessica M Bryant, Clément Regnault, Christine Scheidig-Benatar, Sebastian Baumgarten, Julien Guizetti, Artur Scherf

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Applications of CRISPR in Parasitology.Current pharmaceutical biotechnology · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. CRISPR/Cas9 Editing of the Plasmodium falciparum Genome.Methods in molecular biology (Clifton, N.J.) · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Plasmodium falciparum In Vitro Drug Resistance Selections and Gene Editing.Methods in molecular biology (Clifton, N.J.) · 2019
    Article
  17. Variant antigen repertoires inGenome research · 2018
    Article
  18. Review
  19. Frontiers in microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jessica M BryantUnité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, Paris, France jessica.bryant@pasteur.fr julien.guizetti@gmail.com.
Clément RegnaultUnité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, Paris, France.
Christine Scheidig-BenatarUnité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, Paris, France.
Sebastian BaumgartenUnité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, Paris, France.
Julien GuizettiUnité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, Paris, France jessica.bryant@pasteur.fr julien.guizetti@gmail.com.
Artur ScherfUnité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, Paris, France.
Inserm · FRCentre National de la Recherche Scientifique · FRInstitut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CRISPR-Cas SystemsGene SilencingIntronsTranscriptional ActivationAntigenic VariationAntigens, ProtozoanGene EditingGene Expression RegulationPlasmodium falciparumProtozoan ProteinsAntigens, Protozoanerythrocyte membrane protein 1, Plasmodium falciparumProtozoan ProteinsVAR2CSA protein, Plasmodium falciparumantigenic variationCRISPR/Cas9Plasmodium falciparumtranscriptional regulationvar genes

Identifiers

PMID28698275
PMCPMC5513710
OpenAlexW2735079828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.