Evidence map›Paper›PMID 28698270›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Association between Endothelin-1 Levels and Kidney Disease among Blacks.

Casey M Rebholz, Jane L Harman, Morgan E Grams, Adolfo Correa, Daichi Shimbo, Josef Coresh, Bessie A Young

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Casey M RebholzDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; crebhol1@jhu.edu.
Jane L HarmanProgram in Prevention and Population Sciences, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Morgan E GramsWelch Center for Prevention, Epidemiology, and Clinical Research, Baltimore, Maryland.
Adolfo CorreaDepartments of Pediatrics and.
Daichi ShimboDepartment of Medicine, Columbia University Medical Center, New York, New York; and.
Josef CoreshDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Bessie A YoungDivision of Nephrology, Department of Medicine, Veterans Affairs Puget Sound Health Care System and the University of Washington, Seattle, Washington.
Welch Foundation · USColumbia University Irving Medical Center · USJohns Hopkins University · USNational Institutes of Health · USUniversity of Mississippi Medical Center · USVA Puget Sound Health Care System · US

Funding

CKD-Targeted Analyses of the Jackson Heart StudyR01DK102134 · NIDDK · UNIVERSITY OF WASHINGTON · PI YOUNG, BESSIE ANN · 2013 to 2015
$829k
Metabolomics for Identifying Biomarkers of Dietary Intake & Kidney Disease ProgressionK01DK107782 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI REBHOLZ, CASEY MARIE · 2016 to 2020
$778k
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CNIDDK NIH HHS K01 DK107782NIDDK NIH HHS R01 DK102134
6 · The paper itself

Abstract

Endothelin-1, a marker of endothelial dysfunction, is a potent vasoconstrictor released by endothelial cells and an important regulator of renal physiology. It is not known whether elevated serum levels of endothelin-1 indicate future risk of kidney disease in the general population. In participants in the Jackson Heart Study, a community-based observational study of cardiovascular risk in black adults, we measured serum endothelin-1 level at baseline (2000-2004;

Indexed as

Black PeopleAdultAgedAged, 80 and overDisease ProgressionEndothelin-1FemaleGlomerular Filtration RateHumansMaleMiddle AgedProspective StudiesRenal Insufficiency, ChronicYoung AdultEndothelin-1Chronic kidney diseaseendothelin-1Epidemiology and outcomes

Identifiers

PMID28698270
PMCPMC5661281
OpenAlexW2736116220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.