ArticleRespiratory care2017
Spirometry, Static Lung Volumes, and Diffusing Capacity.
Article in Respiratory care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Is there a correlation between the changes in airway inflammation and the changes in respiratory mechanics after vaping in patients with asthma?World journal of methodology · 2024Trial
- Trial
- Prediction of air trapping or pulmonary hyperinflation by forced spirometry in COPD patients: results from COSYCONET.ERJ open research · 2020Article
- GPs should not try to detect mild COPD.NPJ primary care respiratory medicine · 2020Article
- FEVRespiratory care · 2020Article
- Physiological Network From Anthropometric and Blood Test Biomarkers.Frontiers in physiology · 2020Article
- Re-evaluation of combination therapy in chronic obstructive pulmonary disease (COPD).Respiratory medicine · 2019Article
- Article
- Spirometric impairments, cardiovascular outcomes, and noncardiovascular death in older persons.Respiratory medicine · 2018Article
- Article
- Diffusing capacity in normal-for-age spirometry and spirometric impairments, using reference equations from the global lung function initiative.Respiratory medicineArticle
- GLI-12 Reference Values versus Fixed 0.7 Ratio for the Detection of Airflow Obstruction in the Presence of Lung Hyperinflation.Biomedicine hubArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundSpirometric Z-scores from the Global Lung Initiative (GLI) rigorously account for age-related changes in lung function and are thus age-appropriate when establishing spirometric impairments, including a restrictive pattern and air-flow obstruction. However, GLI-defined spirometric impairments have not yet been evaluated regarding associations with static lung volumes (total lung capacity [TLC], functional residual capacity [FRC], and residual volume [RV]) and gas exchange (diffusing capacity).
methodsWe performed a retrospective review of pulmonary function tests in subjects ≥40 y old (mean age 64.6 y), including pre-bronchodilator measures for: spirometry (
resultsRelative to normal spirometry, restrictive-pattern had lower adj
conclusionsA GLI-defined spirometric restrictive pattern is strongly associated with a restrictive ventilatory defect (decreased TLC, FRC, and RV), while GLI-defined spirometric air-flow obstruction is strongly associated with hyperinflation (increased FRC) and air trapping (increased RV and RV/TLC). Both spirometric impairments were strongly associated with impaired gas exchange (decreased hemoglobin-adjusted single-breath diffusing capacity).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.