Evidence map›Paper›PMID 28698229›Full record

ArticlePhysiological genomics2017

Changes in the phosphoproteome of brown adipose tissue during hibernation in the ground squirrel,

Gaëtan Herinckx, Nusrat Hussain, Fred R Opperdoes, Kenneth B Storey, Mark H Rider, Didier Vertommen

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Gaëtan Herinckxde Duve Institute, Université catholique de Louvain, Brussels, Belgium; and.
Nusrat Hussainde Duve Institute, Université catholique de Louvain, Brussels, Belgium; and.
Fred R Opperdoesde Duve Institute, Université catholique de Louvain, Brussels, Belgium; and.
Kenneth B StoreyInstitute of Biochemistry and Department of Biology, Carleton University, Ottawa, Ontario, Canada.
Mark H Riderde Duve Institute, Université catholique de Louvain, Brussels, Belgium; and.
Didier Vertommende Duve Institute, Université catholique de Louvain, Brussels, Belgium; and didier.vertommen@uclouvain.be.ORCID http://orcid.org/0000-0001-7648-8282
de Duve Institute · BECarleton University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammalian hibernation is characterized by metabolic rate depression and a strong decrease in core body temperature that together create energy savings such that most species do not have to eat over the winter months. Brown adipose tissue (BAT), a thermogenic tissue that uses uncoupled mitochondrial respiration to generate heat instead of ATP, plays a major role in rewarming from deep torpor. In the present study we developed a label-free liquid chromatography mass spectrometry (LC-MS) strategy to investigate both differential protein expression and protein phosphorylation in BAT extracts from euthermic vs. hibernating ground squirrels (

Indexed as

Adipose Tissue, BrownAnimalsChromatography, LiquidHibernationMalePhosphopeptidesPhosphoproteinsPhosphorylationProteomeProteomicsSciuridaeTandem Mass SpectrometryPhosphopeptidesPhosphoproteinsProteomeAMPKHSLmetabolic depressionmitochondrial protein expressionperilipinprotein phosphorylation

Identifiers

PMID28698229
PMCPMC5625268
OpenAlexW2735008471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.