Evidence map›Paper›PMID 28698108›Full record

ReviewNeuroImage2018

Imaging at ultrahigh magnetic fields: History, challenges, and solutions.

Kamil Uğurbil

Abstract readHistorical ArticleReview
In one paragraph

Review in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 164 citations in OpenAlex.

  1. Article
  2. Article
  3. Magnetic resonance imaging.Science advances · 2026
    Review
  4. Mesoscale Whole-Brain TMagnetic resonance in medicine · 2026
    Article
  5. Article
  6. Article
  7. 10.5 T In Vivo Head Imaging With Universal RF Shimming.Magnetic resonance in medicine · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Kamil UğurbilCenter for Magnetic Resonance Research (CMRR), University of Minnesota Medical School, Minneapolis, MN 55455, USA. Electronic address: kamil@cmrr.umn.edu.
University of Minnesota · US

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
ZOOMED FUNCT IMAGING IN HUMAN BRAIN AT 7T W/ SIMULT HIGH SPATIAL &TEMPORAL RESP41RR008079 · NCRR · UNIVERSITY OF MINNESOTA TWIN CITIES · PI VAN DE MOORTELE, PIERRE-FRANCOIS · 1993 to 2011
$16.3M
Neuroscience Cores For MR Studies of the BrainP30NS057091 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2006 to 2011
$8.5M
NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
Neurons, Vessels and Voxels: Multi-modal Imaging of Layer Specific SignalsR01MH111447 · NIMH · UNIVERSITY OF MINNESOTA · PI KARA, PRAKASH, NASELARIS, THOMAS P · 2016 to 2020
$5.0M
Institutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2M
MULTICHANNEL TRANSMIT FRONTEND FOR 7 TESLAS10RR026783 · NCRR · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2009 to 2009
$500k
NCRR NIH HHS P41 RR008079NCRR NIH HHS S10 RR026783NIBIB NIH HHS P41 EB015894NIMH NIH HHS R01 MH111447NIMH NIH HHS U54 MH091657NINDS NIH HHS P30 NS057091NINDS NIH HHS P30 NS076408
6 · The paper itself

Abstract

Following early efforts in applying nuclear magnetic resonance (NMR) spectroscopy to study biological processes in intact systems, and particularly since the introduction of 4 T human scanners circa 1990, rapid progress was made in imaging and spectroscopy studies of humans at 4 T and animal models at 9.4 T, leading to the introduction of 7 T and higher magnetic fields for human investigation at about the turn of the century. Work conducted on these platforms has provided numerous technological solutions to challenges posed at these ultrahigh fields, and demonstrated the existence of significant advantages in signal-to-noise ratio and biological information content. Primary difference from lower fields is the deviation from the near field regime at the radiofrequencies (RF) corresponding to hydrogen resonance conditions. At such ultrahigh fields, the RF is characterized by attenuated traveling waves in the human body, which leads to image non-uniformities for a given sample-coil configuration because of destructive and constructive interferences. These non-uniformities were initially considered detrimental to progress of imaging at high field strengths. However, they are advantageous for parallel imaging in signal reception and transmission, two critical technologies that account, to a large extend, for the success of ultrahigh fields. With these technologies and improvements in instrumentation and imaging methods, today ultrahigh fields have provided unprecedented gains in imaging of brain function and anatomy, and started to make inroads into investigation of the human torso and extremities. As extensive as they are, these gains still constitute a prelude to what is to come given the increasingly larger effort committed to ultrahigh field research and development of ever better instrumentation and techniques.

Indexed as

Magnetic FieldsAnimalsBrainHistory, 20th CenturyHistory, 21st CenturyHumansMagnetic Resonance ImagingNeuroimaging

Identifiers

PMID28698108
PMCPMC5758441
OpenAlexW2729638236

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.