Evidence map›Paper›PMID 28697836›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2017

[Association between IL-6 C-572G and susceptibility to spontaneous preterm birth].

Xiao Yang, Wei Peng, Li-Na Zhu, Xiao-Ai Zhang, Yan Wang

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In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Xiao YangDevelopmental Biology Laboratory, Bayi Children's Hospital Affiliated to People's Liberation Army Beijing General Hospital, Beijing 100700, China. 001wangyan@sina.com.
Wei Peng
Li-Na Zhu
Xiao-Ai Zhang
Yan Wang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the association between the genetic polymorphism of IL-6 C-572G and susceptibility to spontaneous preterm birth (SPTB).

methodsThe subjects were from Beijing and the surrounding areas of Beijing. This case-control study enrolled 569 SPTB infants, including 56 extremely preterm (<28 weeks of gestation), 166 very preterm (28-31

resultsCompared with the CC genotypes, the IL-6 C-572G G-positive genotype (CG+GG genotype) was significantly associated with an increased susceptibility to moderate to late SPTB (OR=1.35, 95%CI: 1.01-1.80, P=0.04).

conclusionsAmong the Chinese population, IL-6 C-572G polymorphism is associated with susceptibility to moderate to late SPTB.

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideCase-Control StudiesFemaleGenotypeHumansInfant, NewbornInterleukin-6PregnancyPremature BirthIL6 protein, humanInterleukin-6

Identifiers

PMID28697836
PMCPMC7389923

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.