Evidence map›Paper›PMID 28697802›Full record

SynthesisCritical care (London, England)2017

Outcomes of subsyndromal delirium in ICU: a systematic review and meta-analysis.

Rodrigo B Serafim, Marcio Soares, Fernando A Bozza, José R Lapa E Silva, Felipe Dal-Pizzol, Maria Carolina Paulino, Pedro Povoa, Jorge I F Salluh

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Critical care (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03813459 (Subsyndromal Delirium in Intensive Care Unit, a Multicenter Study), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03813459 completednot on this mapstarted 2018, after this paper: background citation

Subsyndromal Delirium in Intensive Care Unit, a Multicenter Study

TypeobservationalSponsorCentro Hospitalar Lisboa OcidentalRan2018 to 2020Enrolled400ConditionsDelirium
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Diagnostic Test Accuracy of the 4AT for Delirium Detection: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Rodrigo B SerafimInstituto D'Or de pesquisa e ensino, Rua Diniz Cordeiro, 30 Botafogo, Rio de Janeiro, RJ 22281-100, Brasil. rodrigobserafim@gmail.com.
Marcio SoaresInstituto D'Or de pesquisa e ensino, Rua Diniz Cordeiro, 30 Botafogo, Rio de Janeiro, RJ 22281-100, Brasil.
Fernando A BozzaInstituto D'Or de pesquisa e ensino, Rua Diniz Cordeiro, 30 Botafogo, Rio de Janeiro, RJ 22281-100, Brasil.
José R Lapa E SilvaHospital Universitário Clementino Fraga Filho/Instituto de Doenças do Tórax, Universidade Federal do Rio de Janeiro, Faculdade de Medicina, Av. Prof. Rodolpho Paulo Rocco, 255, Ilha do Fundão, 21941913, Rio de Janeiro, RJ, Brasil.
Felipe Dal-PizzolLaboratório de patofisiologia experimental, Programa de graduação em ciências médicas, Universidade do Extremos Sul Catarinense, Avenida Universitária, 1105, C-postal: 3167, 88806-000, Criciuma, SC, Brasil.
Maria Carolina PaulinoUnidade de Cuidados Intensivos Polivalente, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, Estrada do Forte do Alto do Duque, 1449-005, Lisboa, Portugal.
Pedro PovoaUnidade de Cuidados Intensivos Polivalente, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, Estrada do Forte do Alto do Duque, 1449-005, Lisboa, Portugal.
Jorge I F SalluhInstituto D'Or de pesquisa e ensino, Rua Diniz Cordeiro, 30 Botafogo, Rio de Janeiro, RJ 22281-100, Brasil.
Centro Hospitalar de Lisboa Ocidental · PTUniversidade Federal do Rio de Janeiro · BRD’Or Institute for Research and Education · BRFundação Oswaldo Cruz · BRHospital Universitário Clementino Fraga Filho · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubsyndromal delirium (SSD) is a frequent condition and has been commonly described as an intermediate stage between delirium and normal cognition. However, the true frequency of SSD and its impact on clinically relevant outcomes in the intensive care unit (ICU) remains unclear.

methodsWe performed a systematic search in PubMed, Embase, CINAHL, Cochrane Library, and PsychINFO, with no language restrictions, up to 1 October 2016 to identify publications that evaluated SSD in ICU patients.

resultsThe six eligible studies were evaluated. SSD was present in 950 (36%) patients. Four studies evaluated only surgical patients. Four studies used the Intensive Care Delirium Screening Checklist (ICDSC) and two used the Confusion Assessment Method (CAM) score to diagnose SSD. The meta-analysis showed an increased hospital length of stay (LOS) in SSD patients (0.31, 0.12-0.51, p = 0.002; I

conclusionsSSD occurs in one-third of the ICU patients and has limited impact on the outcomes. The current literature concerning SSD is composed of small-sample studies with methodological differences, impairing a clear conclusion about the association between SSD and progression to delirium or worse ICU clinical outcomes.

Indexed as

Decision Support TechniquesAdultChecklistCritical IllnessDeliriumHospital MortalityHumansIntensive Care UnitsLength of StayCritically illDeliriumICUSubsyndromal delirium

Identifiers

PMID28697802
PMCPMC5506578
OpenAlexW2735294190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.