Evidence map›Paper›PMID 28697442›Full record

ArticleBiosensors & bioelectronics2017

Portable amperometric immunosensor for histamine detection using Prussian blue-chitosan-gold nanoparticle nanocomposite films.

Xiu-Xiu Dong, Jin-Yi Yang, Lin Luo, Yi-Feng Zhang, Chuanbin Mao, Yuan-Ming Sun, Hong-Tao Lei, Yu-Dong Shen, Ross C Beier, Zhen-Lin Xu

Abstract read
In one paragraph

Article in Biosensors & bioelectronics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  8. Detection of Acrylamide in Foodstuffs by Nanobody-Based Immunoassays.Journal of agricultural and food chemistry · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
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  16. Carbon Dots-Modified Nanoporous Membrane and FeMolecules (Basel, Switzerland) · 2019
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiu-Xiu DongGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Guangzhou 510642, China.
Jin-Yi YangGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Guangzhou 510642, China.
Lin LuoGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Guangzhou 510642, China.
Yi-Feng ZhangGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Guangzhou 510642, China.
Chuanbin MaoDepartment of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK 73019, USA; School of Materials Science and Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, China. Electronic address: cbmao@ou.edu.
Yuan-Ming SunGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Guangzhou 510642, China.
Hong-Tao LeiGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Guangzhou 510642, China.
Yu-Dong ShenGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Guangzhou 510642, China.
Ross C BeierUS Department of Agriculture, Agricultural Research Service, Southern Plains Agricultural Research Center, Food and Feed Safety Research Unit, College Station, TX 77845, USA.
Zhen-Lin XuGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Guangzhou 510642, China. Electronic address: jallent@163.com.

Funding

Virus-based nanoparticles for detecting breast cancer biomarkersR01EB021339 · NIBIB · UNIVERSITY OF OKLAHOMA · PI CAO, BINRUI · 2016 to 2019
$1.4M
Hiring Non-toxic Virus Nanoparticles to Count Cancer Biomarker MoleculesR21CA195607 · NCI · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2015 to 2016
$359k
NCI NIH HHS R21 CA195607NIBIB NIH HHS R01 EB021339
6 · The paper itself

Abstract

Histamine (HA) is a biogenic amine that can accumulate to high concentration levels in food as a result of microbial activity and can cause toxic effects in consumers. In this work, a portable electrochemical immunosensor capable of detecting HA with high sensitivity and selectivity was developed. Prussian blue-chitosan-gold nanoparticle (PB-CS-AuNP) nanocomposite films with excellent biocompatibility were synthesized and characterized by scanning electron microscopy and energy dispersive X-ray analysis. The PB-CS-AuNP were coated onto a screen-printed electrode by one-step electrodeposition and used to conjugate the HA ovalbumin conjugate (HA-Ag). HA was determined by a competition between the coating HA-Ag and the HRP labeled HA antibody (HRP-HA-Ab). After careful optimization of assay conditions and Box-Behnken analysis, the developed immunosensor showed a linear range from 0.01 to 100μg/mL for HA in fish samples. The average recoveries from spiked samples ranged from 97.25% to 105%. The biosensor also showed good specificity, reproducibility, and stability, indicating its potential application in monitoring HA in a simple and low cost manner.

Indexed as

Biosensing TechniquesChitosanElectrochemical TechniquesGoldHistamineImmunoassayMetal NanoparticlesNanocompositesNanotubes, CarbonChitosanGoldHistamineNanotubes, CarbonFood analysisHistamineImmunosensorPrussian blue-chitosan-gold nanoparticles

Identifiers

PMID28697442
PMCPMC5762249

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.