ArticlePancreas2017
Effect of Serum Triglycerides on Clinical Outcomes in Acute Pancreatitis: Findings From a Regional Integrated Health Care System.
Article in Pancreas, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07720232 (Effect of Bacillus Subtilis and Enterococcus Faecium Combination Therapy Combined With Conventional Lipid-Lowering Treatment on Triglyceride Levels in Patients With Hypertriglyceridemic Acute Pancreatitis), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Bacillus Subtilis and Enterococcus Faecium Combination Therapy Combined With Conventional Lipid-Lowering Treatment on Triglyceride Levels in Patients With Hypertriglyceridemic Acute Pancreatitis: A Prospective Randomized Controlled Trial
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Assessment of the course of acute pancreatitis in the light of aetiology: a systematic review and meta-analysis.Scientific reports · 2020Pooled it
- The effect of serum triglyceride concentration on the outcome of acute pancreatitis: systematic review and meta-analysis.Scientific reports · 2018Pooled it
- Insulin is central, plasmapheresis is salvage: clinical spectrum and management of severe hypertriglyceridemia in 21 children with diabetic ketoacidosis.Frontiers in endocrinology · 2026Article
- Multisystem laboratory changes before and after blood purification in acute pancreatitis: a real-world descriptive analysis of 141 cases.Frontiers in medicine · 2026Article
- Triglyceride lowering in patients with different severities of hypertriglyceridaemia-associated acute pancreatitis: secondary analysis of a multicentre, prospective cohort study.BMJ open gastroenterology · 2025Article
- Ultra-early indicators of acute hypertriglyceridemic pancreatitis may influence treatment decision-making.Scientific reports · 2025Article
- Timely Application of Plasma Exchange to Correct Acute Pancreatitis Related to Serum Triglyceride Levels: A Report of 6 Cases and a Literature Review.The American journal of case reports · 2024Review
- Relationship of circulating levels of long-chain fatty acids to persistent organ failure in acute pancreatitis.American journal of physiology. Gastrointestinal and liver physiology · 2023Article
- High Triglyceride-Glucose Index Is Associated with Poor Prognosis in Patients with Acute Pancreatitis.Digestive diseases and sciences · 2023Article
- Evidence-Based Approach to the Surgical Management of Acute Pancreatitis.Surgery journal (New York, N.Y.) · 2022Review
- Hyperlipemia pancreatitis onset time affects the association between elevated serum triglyceride levels and disease severity.Lipids in health and disease · 2022Article
- Neutrophil-Lymphocyte Ratio in Patients with Hypertriglyceridemic Pancreatitis Predicts Persistent Organ Failure.Gastroenterology research and practice · 2022Article
- Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis.Disease markers · 2022Article
- Article
- Pancreatitis: TIGAR-O Version 2 Risk/Etiology Checklist With Topic Reviews, Updates, and Use Primers.Clinical and translational gastroenterology · 2019Review
- Acute Pancreatitis: A Multifaceted Set of Organelle and Cellular Interactions.Gastroenterology · 2019Review
- Influence of Ambulatory Triglyceride Levels on Risk of Recurrence in Patients with Hypertriglyceridemic Pancreatitis.Digestive diseases and sciences · 2019Article
- Hypertriglyceridemia-Related Pancreatitis In Patients With Type 2 Diabetes: Links And Risks.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Moderate Hypertriglyceridemia Causing Recurrent Pancreatitis: A Case Report and the Literature Review.Case reports in gastrointestinal medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
objectivesThe aim of this study was to evaluate the effect of serum triglycerides on the development of multiple or persistent organ failure in patients with acute pancreatitis.
methodsA retrospective cohort study was conducted among patients hospitalized for acute pancreatitis between 2006 and 2013. Triglyceride levels measured before and within 72 hours of admission were compared. In addition, the effect of triglyceride levels on the development of multiple or persistent organ failure during hospitalization for acute pancreatitis was assessed.
resultsAmong 2519 patients, 267 patients (10.6%) developed organ failure, of which 75 patients developed multiple system organ failure and 82 patients developed persistent organ failure. Triglyceride levels in patients who developed organ failure were initially much higher than in patients who did not develop organ failure, but by 72 hours into admission, approached levels of patients who did not develop organ failure. Approximately 8% of patients had triglyceride levels greater than 500 mg/dL, the majority of which had similarly high levels before admission.
conclusionsIncreased triglyceride levels were associated with the development of multiple or persistent organ failure among patients hospitalized with acute pancreatitis. Patients with high triglyceride levels at the time of admission were likely to have high triglyceride levels before admission.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.