Evidence map›Paper›PMID 28696820›Full record

ReviewSmall GTPases2018

Viral interactions with host cell Rab GTPases.

Paul Spearman

Open access · hybridAbstract readReview
In one paragraph

Review in Small GTPases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. The Procaine-Based ProcClusterInternational journal of molecular sciences · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Host Factor Rab4b PromotesMicroorganisms · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Paul Spearmana Infectious Diseases, Cincinnati Children's Hospital Medical Center , Cincinnati , OH , USA.
Cincinnati Children's Hospital Medical Center · US

Funding

Viral and Cellular Determinants of HIV-1 AssemblyR01GM111027 · NIGMS · EMORY UNIVERSITY · PI SPEARMAN, PAUL W. · 2013 to 2019
$1.7M
NIGMS NIH HHS R01 GM111027
6 · The paper itself

Abstract

Viruses are obligate intracellular parasites that utilize cellular machinery for many aspects of their replication cycles. Enveloped viruses generally rely upon host vesicular trafficking machinery to direct their structural proteins and genomes to sites of virus replication, assembly, and budding. Rab GTPases have been implicated in the replication of many important viral pathogens infecting humans. This review provides a summary of virus-Rab protein interactions, with a particular focus on the role of Rab-related trafficking pathways on late events in the lifecycle of herpesviruses and of HIV-1.

Indexed as

Host-Pathogen InteractionsVirus Physiological PhenomenaHumansrab GTP-Binding ProteinsVirusesVirus Replicationrab GTP-Binding ProteinsCMVHIV-1HSV-1Rab GTPasesRSVviral glycoproteinvirus assembly

Identifiers

PMID28696820
PMCPMC5902213
OpenAlexW2734837201

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.