Evidence map›Paper›PMID 28696777›Full record

ReviewJournal of alternative and complementary medicine (New York, N.Y.)2017

Therapeutic Uses of Triphala in Ayurvedic Medicine.

Christine Tara Peterson, Kate Denniston, Deepak Chopra

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of alternative and complementary medicine (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06575335 (Antibacterial Efficacy of Triphala Tooth Wipes in Reduction of Streptococcus Mutans Colonies in Differently Abled Children- A Randomized Clinical Trial), which is not on this map. Cited by 111 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06575335 nacompletednot on this mapstarted 2024, after this paper: background citation

Antibacterial Efficacy of Triphala Tooth Wipes in Reduction of Streptococcus Mutans Colonies in Differently Abled Children- A Randomized Clinical Trial

TypeinterventionalSponsorDow University of Health SciencesRan2024 to 2024Enrolled60ConditionsPlaque ControlArmsTriphala Tooth Wipe, Chlorhexidine Tooth Wipe
3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Evaluation of the Effects of Gastro Protect as an Alternative Medicine on Gastritis and Other Gastrointestinal Symptoms.Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) · 2024
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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christine Tara Peterson1 Department of Family Medicine and Public Health, UC San Diego School of Medicine, Center of Excellence for Research and Training in Integrative Health , La Jolla, CA.
Kate Denniston3 Department of Naturopathic Medicine, Bastyr University , San Diego, CA.
Deepak Chopra1 Department of Family Medicine and Public Health, UC San Diego School of Medicine, Center of Excellence for Research and Training in Integrative Health , La Jolla, CA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this article is to review the current literature on the therapeutic uses and efficacy of Triphala. Herbal remedies are among the most ancient medicines used in traditional systems of healthcare such as Ayurveda. Triphala, a well-recognized and highly efficacious polyherbal Ayurvedic medicine consisting of fruits of the plant species Emblica officinalis (Amalaki), Terminalia bellerica (Bibhitaki), and Terminalia chebula (Haritaki), is a cornerstone of gastrointestinal and rejuvenative treatment.

methodsA search of the PubMed database was conducted.

resultsIn addition, numerous additional therapeutic uses described both in the Ayurvedic medical literature and anecdotally are being validated scientifically. In addition to laxative action, Triphala research has found the formula to be potentially effective for several clinical uses such as appetite stimulation, reduction of hyperacidity, antioxidant, anti-inflammatory, immunomodulating, antibacterial, antimutagenic, adaptogenic, hypoglycemic, antineoplastic, chemoprotective, and radioprotective effects, and prevention of dental caries. Polyphenols in Triphala modulate the human gut microbiome and thereby promote the growth of beneficial Bifidobacteria and Lactobacillus while inhibiting the growth of undesirable gut microbes. The bioactivity of Triphala is elicited by gut microbiota to generate a variety of anti-inflammatory compounds.

conclusionsThis review summarizes recent data on pharmacological properties and clinical effects of Triphala while highlighting areas in need of additional investigation and clinical development.

Indexed as

Medicine, AyurvedicPlant ExtractsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsHumansPhytotherapyAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsPlant Extractstriphalaanti-inflammatoryantimicrobialantioxidantAyurvedaimmunomodulatingmicrobiota

Identifiers

PMID28696777
PMCPMC5567597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.