ArticleThe ISME journal2017
Metagenomic binning of a marine sponge microbiome reveals unity in defense but metabolic specialization.
Article in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.
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Who cites it
84 citing papers in PubMed, 158 citations in OpenAlex.
- Low Abundance Taxa Show Diverse Microbial Symbiotic Interactions With the Freshwater Sponge, Radiospongilla crateriformis, Pre and Post Gemmulation.Environmental microbiology reports · 2026Article
- Diel transcriptional dynamics of a marine sponge and its microbiome in a natural environment.Animal microbiome · 2026Article
- Chemical richness and diversity of uncultivated 'Entotheonella' symbionts in marine sponges.Nature chemical biology · 2026Article
- New insights into the microbiome of the deep-sea spongeMicrobial genomics · 2026Article
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- Functional Genomic Characteristics of Marine Sponge-AssociatedMicroorganisms · 2025Article
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- Microbial communities associated with marine sponges from diverse geographic locations harbor biosynthetic novelty.Applied and environmental microbiology · 2024Article
- The unique and enigmatic spirochete symbiont of latrunculid sponges.bioRxiv : the preprint server for biology · 2024Article
- Unveiling microbial guilds and symbiotic relationships in Antarctic sponge microbiomes.Scientific reports · 2024Article
- Microbiome profile of the Antarctic clam Laternula elliptica.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Proteomes of native and non-native symbionts reveal responses underpinning host-symbiont specificity in the cnidarian-dinoflagellate symbiosis.The ISME journal · 2024Article
- The archaeome in metaorganism research, with a focus on marine models and their bacteria-archaea interactions.Frontiers in microbiology · 2024Article
- Metagenomic insights into jellyfish-associated microbiome dynamics during strobilation.ISME communications · 2024Article
- Candidatus Nemesobacterales is a sponge-specific clade of the candidate phylum Desulfobacterota adapted to a symbiotic lifestyle.The ISME journal · 2023Article
- Multi-environment ecogenomics analysis of the cosmopolitan phylum Gemmatimonadota.Microbiology spectrum · 2023Article
- Extracts from Wallis Sponges InhibitMicroorganisms · 2023Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marine sponges are ancient metazoans that are populated by distinct and highly diverse microbial communities. In order to obtain deeper insights into the functional gene repertoire of the Mediterranean sponge Aplysina aerophoba, we combined Illumina short-read and PacBio long-read sequencing followed by un-targeted metagenomic binning. We identified a total of 37 high-quality bins representing 11 bacterial phyla and two candidate phyla. Statistical comparison of symbiont genomes with selected reference genomes revealed a significant enrichment of genes related to bacterial defense (restriction-modification systems, toxin-antitoxin systems) as well as genes involved in host colonization and extracellular matrix utilization in sponge symbionts. A within-symbionts genome comparison revealed a nutritional specialization of at least two symbiont guilds, where one appears to metabolize carnitine and the other sulfated polysaccharides, both of which are abundant molecules in the sponge extracellular matrix. A third guild of symbionts may be viewed as nutritional generalists that perform largely the same metabolic pathways but lack such extraordinary numbers of the relevant genes. This study characterizes the genomic repertoire of sponge symbionts at an unprecedented resolution and it provides greater insights into the molecular mechanisms underlying microbial-sponge symbiosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.