Evidence map›Paper›PMID 28696257›Full record

ArticleThe Journal of biological chemistry2017

Transient and dynamic DNA supercoiling potently stimulates the

Xiaoduo Zhi, Samantha Dages, Kelley Dages, Yingting Liu, Zi-Chun Hua, John Makemson, Fenfei Leng

Open access · hybridAbstract readComparative Study
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

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  11. Divergently Transcribed ncRNAs inFrontiers in molecular biosciences · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Xiaoduo ZhiFrom the Biomolecular Sciences Institute and.
Samantha DagesFrom the Biomolecular Sciences Institute and.
Kelley DagesFrom the Biomolecular Sciences Institute and.
Yingting LiuFrom the Biomolecular Sciences Institute and.
Zi-Chun Huathe School of Life Sciences, Nanjing University, Nanjing 210023, Jiangsu, China.
John MakemsonBiological Sciences, Florida International University, Miami, Florida 33199 and.
Fenfei LengFrom the Biomolecular Sciences Institute and lengf@fiu.edu.
Nanjing University · CNFlorida International University · US

Funding

Targeting transcription-coupled DNA supercoiling for discovering antibiotics against bacterial DNA gyraseR21AI125973 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI LENG, FENFEI · 2017 to 2018
$478k
Transcription-Coupled DNA SupercoilingR15GM109254 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI LENG, FENFEI · 2014 to 2014
$317k
NIAID NIH HHS R21 AI125973NIGMS NIH HHS R15 GM109254
6 · The paper itself

Abstract

The inactive prokaryotic

Indexed as

Gene Expression Regulation, BacterialPoint MutationPromoter Regions, GeneticTranscriptional ActivationChromatin Assembly and DisassemblyDNA, BacterialDNA, CircularDNA-Directed RNA PolymerasesDNA, RecombinantDNA, SuperhelicalEscherichia coliGene DeletionKineticsLeucineLuciferases, FireflyOperonbacteriophage T7 RNA polymeraseDNA, BacterialDNA, CircularDNA-Directed RNA PolymerasesDNA, RecombinantDNA, SuperhelicalLeucineLuciferases, FireflyRecombinant ProteinsViral Proteinsbacterial transcriptionDNA topoisomeraseDNA topologyEscherichia coli (E. coli)supercoilingthe leu-500 promotertranscription promotertwin supercoiled domain model of transcription

Identifiers

PMID28696257
PMCPMC5582848
OpenAlexW2727452348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.