Evidence map›Paper›PMID 28696256›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

A Novel Subset of Anti-Inflammatory CD138

Shuhong Han, Haoyang Zhuang, Stepan Shumyak, Jingfan Wu, Hui Li, Li-Jun Yang, Westley H Reeves

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. iScience · 2025
    Article
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  5. Article
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  13. Article
  14. Common innate pathways to autoimmune disease.Clinical immunology (Orlando, Fla.) · 2020
    Review
  15. Article
  16. Article
  17. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shuhong HanDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Florida, Gainesville, FL 32610; and.
Haoyang ZhuangDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Florida, Gainesville, FL 32610; and.
Stepan ShumyakDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Florida, Gainesville, FL 32610; and.
Jingfan WuDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Florida, Gainesville, FL 32610; and.ORCID 0000-0001-5182-5369
Hui LiDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL 32610.
Li-Jun YangDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL 32610.
Westley H ReevesDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Florida, Gainesville, FL 32610; and whreeves@ufl.edu.
University of Florida · US

Funding

Pathogenesis on Autoantibodies in Pristane-Induced LupusR01AR044731 · NIAMS · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI REEVES, WESTLEY H · 1997 to 2021
$6.6M
NIAMS NIH HHS R01 AR044731
6 · The paper itself

Abstract

Dead cells accumulating in the tissues may contribute to chronic inflammation. We examined the cause of impaired apoptotic cell clearance in human and murine lupus. Dead cells accumulated in bone marrow from lupus patients but not from nonautoimmune patients undergoing myeloablation, where they were efficiently removed by macrophages (MΦ). Impaired apoptotic cell uptake by MΦ also was seen in mice treated i.p. with pristane (develop lupus) but not mineral oil (MO) (do not develop lupus). The inflammatory response to both pristane and MO rapidly depleted resident (Tim4

Indexed as

PhagocytosisAnimalsAntigens, LyApoptosisBone Marrow CellsCyclic AMP Response Element-Binding ProteinDisease Models, AnimalHumansInflammationInterleukin-10 Receptor alpha SubunitLungLupus Erythematosus, SystemicMacrophages, PeritonealMembrane ProteinsMiceMineral OilAntigens, LyCreb1 protein, mouseCyclic AMP Response Element-Binding ProteinInterleukin-10 Receptor alpha SubunitLy-6C antigen, mouseMarco protein, mouseMembrane ProteinsMineral OilPoly IpristaneReceptors, ImmunologicSdc1 protein, mouseSyndecan-1TerpenesTIM-4 protein, mouseTumor Necrosis Factor-alpha

Identifiers

PMID28696256
PMCPMC5548631
OpenAlexW2735998843

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.