Evidence map›Paper›PMID 28696249›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Haploinsufficiency of the Transcription Factor

Wenguang Feng, Bo Chen, Dongqi Xing, Xingsheng Li, Huma Fatima, Edgar A Jaimes, Paul W Sanders

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  6. Review
  7. Article
  8. Journal of the American Society of Nephrology : JASN · 2017
    Article
4 · The record

Corrections and comments

  • Commented on by
    2017
5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wenguang FengDivisions of Nephrology and Cardiovascular Disease, Departments of Medicine, wenguangfeng@uabmc.edu.
Bo ChenCell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama.
Dongqi XingDivisions of Nephrology and Cardiovascular Disease, Departments of Medicine.
Xingsheng LiDivisions of Nephrology and Cardiovascular Disease, Departments of Medicine.
Huma FatimaCell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama.
Edgar A JaimesRenal Service, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Paul W SandersDivisions of Nephrology and Cardiovascular Disease, Departments of Medicine.
University of Alabama at Birmingham · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
UAB-UCSD O'Brien Core Center for Acute Kidney Injury ResearchP30DK079337 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AGARWAL, ANUPAM · 2008 to 2022
$18.3M
Targeted Cell Therapy for Acute Lung InjuryR56HL128285 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI XING, DONGQI · 2016 to 2016
$368k
Novel Regulators of Vascular DiseaseIP1BX001595 · VA · BIRMINGHAM VA MEDICAL CENTER · PI AGARWAL, ANUPAM, CHEN, YABING · 2013 to 2016
–
BLRD VA IP1 BX001595NCI NIH HHS P30 CA008748NHLBI NIH HHS R56 HL128285NIDDK NIH HHS P30 DK079337NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

Studies using Dahl salt-sensitive (SS) rats identified specific quantitative trait loci that predispose animals to hypertension-associated albuminuria and kidney injury. We explored the hypothesis that kidney-specific expression of the transcription factor

Indexed as

HaploinsufficiencyAnimalsHypertensionKidney DiseasesMaleMutationProto-Oncogene Protein c-ets-1RatsRats, Inbred DahlEts1 protein, ratProto-Oncogene Protein c-ets-1albuminuriaEts-1hypertensionkidney diseasekidney transplantation

Identifiers

PMID28696249
PMCPMC5661288
OpenAlexW2735408277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.