Evidence map›Paper›PMID 28696218›Full record

ArticleGenetics2017

Noncanonical Decapentaplegic Signaling Activates Matrix Metalloproteinase 1 To Restrict Hedgehog Activity and Limit Ectopic Eye Differentiation in

Poonam Aggarwal, Jayati Gera, Saikat Ghosh, Lolitika Mandal, Sudip Mandal

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Poonam AggarwalMolecular Cell and Developmental Biology Laboratory, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, 140306, India.ORCID 0000-0001-8608-8055
Jayati GeraMolecular Cell and Developmental Biology Laboratory, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, 140306, India.ORCID 0000-0002-4744-1546
Saikat GhoshDevelopmental Genetics Laboratory, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, 140306, India.ORCID 0000-0001-6517-8377
Lolitika MandalDevelopmental Genetics Laboratory, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, 140306, India.ORCID 0000-0002-7711-6090
Sudip MandalMolecular Cell and Developmental Biology Laboratory, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, 140306, India sudip@iisermohali.ac.in.ORCID 0000-0002-2211-483X
Indian Institute of Science Education and Research Mohali · IN

Funding

DBT-Wellcome Trust India Alliance 500124-Z-09-ZWellcome Trust
6 · The paper itself

Abstract

One of the pertinent issues associated with cellular plasticity is to understand how the delicate balance between the determined state of cells and the extent to which they can transdetermine is maintained. Employing the well-established model of generating ectopic eyes in developing wing discs of

Indexed as

Signal TransductionAnimalsCell ProliferationCompound Eye, ArthropodDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsEye ProteinsGain of Function MutationGene Expression Regulation, DevelopmentalHedgehog ProteinsLoss of Function MutationMAP Kinase Kinase 4MAP Kinase Kinase KinasesMatrix Metalloproteinase 1Nuclear Proteinsdac protein, DrosophilaDNA-Binding Proteinsdpp protein, DrosophilaDrosophila Proteinseya protein, DrosophilaEye Proteinsey protein, DrosophilaHedgehog ProteinsMAD protein, DrosophilaMAP Kinase Kinase 4MAP Kinase Kinase KinasesMatrix Metalloproteinase 1Nuclear ProteinsTAK1 protein, DrosophilaTranscription FactorsDppDrosophilaectopic eyeHhMmp1

Identifiers

PMID28696218
PMCPMC5586372
OpenAlexW2734870169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.