Evidence map›Paper›PMID 28695538›Full record

ArticleMolecular neurobiology2018

Fgf9

Lillian Garrett, Lore Becker, Jan Rozman, Oliver Puk, Tobias Stoeger, Ali Önder Yildirim, Alexander Bohla, Oliver Eickelberg, Wolfgang Hans, Cornelia Prehn and 11 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 6 institutions in 1 country.

Lillian GarrettInstitutes of Developmental Genetics, Helmholtz Zentrum München, Neuherberg, Germany.
Lore BeckerGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Jan RozmanGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Oliver PukInstitutes of Developmental Genetics, Helmholtz Zentrum München, Neuherberg, Germany.
Tobias StoegerGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Ali Önder YildirimGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Alexander BohlaGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Oliver EickelbergGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Wolfgang HansGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Cornelia PrehnGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Jerzy AdamskiExperimental Genetics, Helmholtz Zentrum München, Neuherberg, Germany.
Thomas KlopstockDepartment of Neurology, Friedrich-Baur Institute, Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany.
Ildikó RáczInstitute of Molecular Psychiatry, Medical Faculty, Universität Bonn, Bonn, Germany.
Andreas ZimmerInstitute of Molecular Psychiatry, Medical Faculty, Universität Bonn, Bonn, Germany.
Martin KlingensporMolecular Nutritional Medicine, Faculty of Life and Food Sciences Weihenstephan, Technische Universität München, Munich, Germany.
Helmut FuchsGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Valerie Gailus-DurnerGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Wolfgang WurstInstitutes of Developmental Genetics, Helmholtz Zentrum München, Neuherberg, Germany.
Martin Hrabě de AngelisGerman Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.
Jochen GrawInstitutes of Developmental Genetics, Helmholtz Zentrum München, Neuherberg, Germany.
Sabine M HölterInstitutes of Developmental Genetics, Helmholtz Zentrum München, Neuherberg, Germany. hoelter@helmholtz-muenchen.de.
Helmholtz Zentrum München · DEGerman Center for Lung Research · DELudwig-Maximilians-Universität München · DEUniversity of Bonn · DEHeinrich Heine University Düsseldorf · DETechnical University of Munich · DE

Funding

German Federal Ministry of Education and Research (BMBF) grant 031A430EGerman Federal Ministry of Education and Research (BMBF) Infrafrontier grant 01KX1012
6 · The paper itself

Abstract

In neuropsychiatric diseases, such as major depression and anxiety, pathogenic vulnerability is partially dictated by a genetic predisposition. The search continues to define this genetic susceptibility and establish new genetic elements as potential therapeutic targets. The fibroblast growth factors (FGFs) could be interesting in this regard. This family of signaling molecules plays important roles in development while also functioning within the adult. This includes effects on aspects of brain function such as neurogenesis and synapse formation. Of this family, Fgf9 is expressed in the adult brain, but its functional role is less well defined. In this study, we examined the role of Fgf9 in different brain functions by analyzing the behavior of Fgf9

Indexed as

MemorySocial BehaviorAnalysis of VarianceAnesthesiaAnimalsAnxietyCorticosteroneDiscrimination, PsychologicalFemaleFibroblast Growth Factor 9HippocampusMaleMiceMice, Mutant StrainsMotor ActivityMutationCorticosteroneFgf9 protein, mouseFibroblast Growth Factor 9Adult neurogenesisBrainFibroblast growth factor 9MiceNeuropsychiatric disease

Identifiers

PMID28695538
OpenAlexW2734953025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.