Evidence map›Paper›PMID 28695471›Full record

ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2017

Ocrelizumab and Other CD20

Jeffrey M Gelfand, Bruce A C Cree, Stephen L Hauser

Open access · bronzeAbstract readReview
In one paragraph

Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 3 pooled it
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 3 syntheses or guidelines pooled it, 199 citations in OpenAlex.

  1. Maternal disease control and pregnancy outcomes with anti-CD20 therapy versus natalizumab in multiple sclerosis: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Neurology(R) neuroimmunology & neuroinflammation · 2026
    Observational
  7. Review
  8. Acta pharmaceutica Sinica. B · 2026
    Article
  9. Article
  10. Observational
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Real-world effectiveness and safety of ofatumumab in relapsing-remitting multiple sclerosis: Insights from naïve and switch patients.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  17. Review
  18. Review
  19. Article
  20. Review

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jeffrey M GelfandMultiple Sclerosis Center, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.
Bruce A C CreeMultiple Sclerosis Center, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.
Stephen L HauserMultiple Sclerosis Center, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA. stephen.hauser@ucsf.edu.
University of California, San Francisco · US

Funding

A Haplotype Map for Multiple SclerosisR01NS049477 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAUSER, STEPHEN L · 2005 to 2014
$15.3M
GENE LINKAGE STUDY OF MULTIPLE SCLEROSIS SIBLING PAIRSR01NS026799 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAUSER, STEPHEN L, OKSENBERG, JORGE R. · 1989 to 2018
$6.8M
NINDS NIH HHS R01 NS026799NINDS NIH HHS R01 NS049477
6 · The paper itself

Abstract

Selective depletion of CD20

Indexed as

Antibodies, Monoclonal, HumanizedAntigens, CD20B-LymphocytesClinical Trials as TopicDisease ProgressionHumansImmunologic FactorsMultiple SclerosisTreatment OutcomeAntibodies, Monoclonal, HumanizedAntigens, CD20Immunologic FactorsocrelizumabB-cell-depleting therapyMultiple sclerosisocrelizumabprogressive MSrelapsing-remitting MSrituximab

Identifiers

PMID28695471
PMCPMC5722762
OpenAlexW2734442974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.