Evidence map›Paper›PMID 28695442›Full record

ArticleCardiovascular engineering and technology2017

Fistula First Initiative: Historical Impact on Vascular Access Practice Patterns and Influence on Future Vascular Access Care.

Timmy Lee

Open access · greenAbstract read
In one paragraph

Article in Cardiovascular engineering and technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 146 citations in OpenAlex.

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  9. Quality Metrics in Dialysis: A Welcome Change for Vascular Access.Advances in kidney disease and health · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Timmy LeeDepartment of Medicine and Division of Nephrology, University of Alabama at Birmingham, 1720 2nd Ave South, Birmingham, AL, 35294-0007, USA. txlee@uab.edu.ORCID http://orcid.org/0000-0002-5305-7268
University of Alabama at Birmingham · US

Funding

UAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4M
Nitric oxide releasing nanomatrix wrap to enhance dialysis fistula maturationR43DK109789 · NIDDK · ENDOMIMETICS, LLC · PI HWANG, PATRICK, LEE, TIMMY C · 2016 to 2016
$429k
The Role of Endothelial Dysfunction in Arteriovenous Fistula MaturationI01BX003387 · VA · BIRMINGHAM VA MEDICAL CENTER · PI LEE, TIMMY C · 2017 to 2020
–
BLRD VA I01 BX003387National Institute of Diabetes and Digestive and Kidney Diseases 1R43DK109789-01NCATS NIH HHS UL1 TR001417NIDDK NIH HHS R43 DK109789U.S. Department of Veterans Affairs 1I01BX003387-01A1
6 · The paper itself

Abstract

The vascular access is the lifeline for the hemodialysis patient. In the United States, the Fistula First Breakthrough Initiative (FFBI) has been influential in improving use of arteriovenous fistulas (AVF) in prevalent hemodialysis patients. Currently, prevalent AVF rates are near the goal of 66% set forth by the original FFBI. However, central venous catheter (CVC) rates remain very high in the United States in patients initiating hemodialysis, nearly exceeding 80%. A new direction of the of the FFBI has focused on strategies to reduce CVC use, and subsequently the FFBI has now been renamed the "Fistula First-Catheter Last Initiative". However, an AVF may not be the best vascular access in all hemodialysis patients, and arteriovenous grafts (AVG) and CVCs may be appropriate and the best access for a subset of hemodialysis patients. Unfortunately, there still remains very little emphasis within vascular access initiatives and guidelines directed towards evaluation of the individual patient context, specifically patients with poor long-term prognoses and short life expectancies, patients with multiple comorbidities, patients who are more likely to die than reach end stage renal disease (ESRD), and patients of elderly age with impaired physical and cognitive function. Given the complexity of medical and social issues in advanced CKD and ESRD patients, planning, selection, and placement of the most appropriate vascular access are ideally managed within a multidisciplinary setting and requires consideration of several factors including national vascular access guidelines. Thus, the evolution of the FFBI should underscore the need for multidisciplinary health teams with a major emphasis placed on "the right access for the right patient" and improving the patient's overall quality of life.

Indexed as

AgedArteriovenous FistulaArteriovenous Shunt, SurgicalCentral Venous CathetersHealth Services AccessibilityHumansNational Health ProgramsQuality of LifeRenal DialysisRenal Insufficiency, ChronicUnited StatesVascular Access DevicesVascular PatencyArteriovenous fistulaArteriovenous graftFistula firstHemodialysis catheterHemodialysis vascular access

Identifiers

PMID28695442
PMCPMC5693683
OpenAlexW2734483105

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.