ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018
Quantification of intramyocardial blood volume with
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Simultaneously quantifyingPhysics in medicine and biology · 2026Article
- Ferumoxytol-Enhanced Myocardial T1 Tracking Using a Hybrid 2D/3D Steady-State MRI Sequence Captures Cyclic Intramyocardial Blood Volume Dynamics.NMR in biomedicine · 2026Article
- Critical review of partial volume correction methods in PET and SPECT imaging: benefits, pitfalls, challenges, and future outlook.European journal of nuclear medicine and molecular imaging · 2026Review
- Ultrafast power Doppler imaging for RV myocardial perfusion assessment: histopathologic correlation andEuropean heart journal. Imaging methods and practice · 2026Article
- Noise-aware dynamic image denoising and positron range correction for Rubidium-82 cardiac PET imaging via self-supervision.Medical image analysis · 2025Article
- The myocardial function index (MFI): An integrated measure of cardiac function in AL-cardiomyopathy.International journal of cardiology. Heart & vasculature · 2024Article
- Article
- Segmentation-Free PVC for Cardiac SPECT Using a Densely-Connected Multi-Dimensional Dynamic Network.IEEE transactions on medical imaging · 2023Article
- Quantification of intramyocardial blood volume usingJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Feasibility study of PET dynamic imaging of [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Microvascular function measurement in mice: From large to small.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Nuclear cardiology in the context of multimodality imaging to detect cardiac toxicity from cancer therapeutics: Established and emerging methods.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Review
- Molecular Imaging of the Heart.Comprehensive Physiology · 2019Review
- Cutaneous Toxicity in a Laboratory Beagle (Comparative medicine · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundCurrently, there is no established non-invasive imaging approach to directly evaluate myocardial microcirculatory function in order to diagnose microvascular disease independent of co-existing epicardial disease. In this work, we developed a methodological framework for quantification of intramyocardial blood volume (IMBV) as a novel index of microcirculatory function with SPECT/CT imaging of
methodsDual-gated myocardial SPECT/CT equilibrium imaging of
resultsThe estimated IMBV with all corrections was 0.15 ± 0.03 for the end-diastolic phase and 0.11 ± 0.03 for the end-systolic phase. The cycle-dependent change in IMBV (ΔIMBV) with all corrections was 23.9 ± 8.6%. Schemes that applied no correction or partial correction resulted in significant over-estimation of IMBV and significant under-underestimation of ΔIMBV. Estimates of IMBV and ΔIMBV using all corrections were consistent with values reported in the literature using invasive techniques. In vivo SPECT estimates of IMBV strongly correlated (R
conclusionsNon-invasive quantification of IMBV is feasible using
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