Evidence map›Paper›PMID 28695343›Full record

Observational studyInternational urogynecology journal2018

Posterior colporrhaphy does not affect the urethral closure mechanism.

Yasmine Khayyami, Gunnar Lose, Niels Klarskov

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International urogynecology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Prolapse reduction deteriorates the urethral closure mechanism.International urogynecology journal · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yasmine KhayyamiDepartment of Obstetrics and Gynecology, University of Copenhagen, Herlev Gentofte Hospital, Herlev Ringvej 75, 2730, Herlev, Copenhagen, Denmark. yasmine.khayyami@regionh.dk.ORCID http://orcid.org/0000-0003-0066-5451
Gunnar LoseDepartment of Obstetrics and Gynecology, University of Copenhagen, Herlev Gentofte Hospital, Herlev Ringvej 75, 2730, Herlev, Copenhagen, Denmark.
Niels KlarskovDepartment of Obstetrics and Gynecology, University of Copenhagen, Herlev Gentofte Hospital, Herlev Ringvej 75, 2730, Herlev, Copenhagen, Denmark.
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisStudies have suggested that a posterior vaginal wall prolapse might compress the urethra and mask stress urinary incontinence (SUI), much like an anterior vaginal wall prolapse. A recent study with urethral pressure reflectometry (UPR) has shown that the urethral closure mechanism deteriorates after anterior colporrhaphy; this could explain the occurrence of postoperative de novo SUI. We hypothesized that urethral pressure would also decrease after posterior colporrhaphy.

methodsThis was a prospective, observational study where women with posterior vaginal wall prolapse ≥stage II were examined before and after posterior colporrhaphy. We performed prolapse staging according to the Pelvic Organ Prolapse Quantification system, UPR measurements at rest, during squeezing and straining, and standardized stress tests with 300 ml saline. The women filled out International Consultation on Incontinence-Urinary incontinence (ICIQ-UI) short forms. The sample size was 18, with a power of 99.9% and a level of significance of 5%. Parameters were compared using paired t tests or Fisher's exact test, where appropriate; p values <0.05 were considered statistically significant.

resultsEighteen women with posterior vaginal wall prolapse ≥stage II were recruited. One woman did not undergo surgery. There were no changes in urethral pressure at rest (p = 0.4), during squeezing (p = 0.2) or straining (p = 0.2), before and after surgery. The results of the stress tests and ICIQ-UI short forms were the same after surgery.

conclusionsThe urethral closure mechanism is not affected by posterior colporrhaphy. Our study does not support the theory that the posterior vaginal wall prolapse compresses the urethra and masks SUI.

Indexed as

AdultAgedFemaleHumansMiddle AgedPostoperative PeriodPreoperative PeriodPressureProspective StudiesUrethraUrinary BladderUrinary Incontinence, StressUterine ProlapsePelvic organ prolapsePosterior colporrhaphyStress urinary incontinenceUrethral pressure reflectometryUrodynamics

Identifiers

PMID28695343
OpenAlexW2734939656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.