ArticleScience advances2017
Peripheral myelin protein 22 alters membrane architecture.
Open access · goldAbstract read
In one paragraph
Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- The neuroprotective effects of progesterone against peripheral neuropathy: a systematic review of non-clinical studies.Metabolic brain disease · 2024Pooled it
- Hypoxia-preconditioned mitochondrial transplantation multidirectionally modulates Schwann cell functions to repair peripheral nerve injury in rats.Journal of orthopaedic translation · 2026Article
- Peripheral Myelin Protein-22 and Its Prominence in Charcot-Marie-Tooth Disease.Chemical reviews · 2026Review
- Longitudinal analysis of lipid changes in the sciatic nerve caused by overexpression of PMP22 in murine models of CMT1A.Journal of lipid research · 2026Article
- Charcot-Marie-Tooth disease type 1E: clinical natural history and molecular impact of PMP22 variants.Brain : a journal of neurology · 2026Article
- Metabolic signatures in sciatic nerve of PMP22 transgenic rats provide insights into the pathogenesis of charcot-marie-tooth disease type 1 A.Scientific reports · 2026Article
- 5-HT1B receptor agonists promote Schwann cell myelination.PloS one · 2026Article
- Characterising PMP22-Proximal Partners in a Schwann Cell Model of Charcot-Marie-Tooth Disease Type1A.Biology · 2025Article
- On the synergy between myelin proteins P0, MBP, and P2 in peripheral nerve major dense line formation.The FEBS journal · 2025Article
- Charcot-Marie-Tooth disease type 1E: Clinical Natural History and Molecular Impact ofmedRxiv : the preprint server for health sciences · 2025Article
- Cystic Fibrosis Modulator Therapies: Bridging Insights from CF to other Membrane Protein Misfolding Diseases.Israel journal of chemistry · 2024Article
- Disrupting the transmembrane domain interface between PMP22 and MPZ causes peripheral neuropathy.iScience · 2024Article
- PMP22 duplication dysregulates lipid homeostasis and plasma membrane organization in developing human Schwann cells.Brain : a journal of neurology · 2024Article
- Feasibility and safety of minimally invasive calcaneal osteotomy (MICO) through a medial approach: a case-control study.Orthopadie (Heidelberg, Germany) · 2024Article
- Preclinical Efficacy of Peripheral Nerve Regeneration by Schwann Cell-like Cells Differentiated from Human Tonsil-Derived Mesenchymal Stem Cells in C22 Mice.Biomedicines · 2023Article
- AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells.Communications medicine · 2023Article
- Infrared Photoactivation Enables Improved Native Top-Down Mass Spectrometry of Transmembrane Proteins.Analytical chemistry · 2023Article
- Mechanisms and treatment strategies of demyelinating and dysmyelinating Charcot-Marie-Tooth disease.Neural regeneration research · 2023Review
- 4-Methylumbelliferone Targets Revealed by Public Data Analysis and Liver Transcriptome Sequencing.International journal of molecular sciences · 2023Article
- Neuron-Schwann cell interactions in peripheral nervous system homeostasis, disease, and preclinical treatment.Frontiers in cellular neuroscience · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 1 country.
Kathleen F MittendorfCenter for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.
Justin T MarinkoCenter for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.ORCID 0000-0002-0473-5229
Cheri M HamptonDivision of Infectious Disease, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0000-0003-0069-8712
Zunlong KeDivision of Infectious Disease, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Arina HadziselimovicCenter for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.ORCID 0000-0001-5758-9328
Jonathan P SchlebachCenter for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.ORCID 0000-0003-0955-7633
Cheryl L LawCenter for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.ORCID 0000-0001-6460-2439
Jun LiDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Elizabeth R WrightDivision of Infectious Disease, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Charles R SandersCenter for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.ORCID 0000-0003-2046-2862
Melanie D OhiCenter for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.
Vanderbilt University · USEmory University · USGeorgia Institute of Technology · USVanderbilt University Medical Center · US
Funding
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0MVanderbilt/Meharry Initiative for Minority Student DvptR25GM062459 · NIGMS · VANDERBILT UNIVERSITY · PI VELEZ EDWARDS, DIGNA R · 2002 to 2020
$10.4MMOLECULAR BIOPHYSICS TRAINING PROGRAM AT VANDERBILTT32GM008320 · NIGMS · VANDERBILT UNIVERSITY · PI CHAZIN, WALTER J. · 1989 to 2023
$7.9MFolding, Misfolding, and Function of PMP22R01NS095989 · NINDS · VANDERBILT UNIVERSITY · PI Bruce D Carter, CHARLES R SANDERS · 2016 to 2026
$4.6MPathophysiology of Conduction Block in HNPP.R01NS066927 · NINDS · WAYNE STATE UNIVERSITY · PI LI, JUN · 2010 to 2019
$3.5MStructural Investigations Of Macromolecular Complexes Critical To hRSV Life CycleR01GM114561 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SANTANGELO, PHILIP J, WRIGHT, ELIZABETH R · 2016 to 2019
$1.6MStructure and Function of Prokaryotic Appendages by Cryo-Electron TomographyR01GM104540 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI WRIGHT, ELIZABETH R · 2013 to 2017
$1.4MStructure, Folding, and Misfolding of PMP22R01NS058815 · NINDS · VANDERBILT UNIVERSITY · PI CARTER, BRUCE D, SANDERS, CHARLES R · 2010 to 2012
$921kStructural Basis for the Partitioning of C99 into Liquid-Ordered Membrane DomainsF32GM110929 · NIGMS · VANDERBILT UNIVERSITY · PI SCHLEBACH, JONATHAN PATRICK · 2014 to 2015
$109kNIAID NIH HHS P30 AI050409NIGMS NIH HHS F32 GM110929NIGMS NIH HHS R01 GM104540NIGMS NIH HHS R01 GM114561NIGMS NIH HHS R25 GM062459NIGMS NIH HHS T32 GM008320NINDS NIH HHS R01 NS058815NINDS NIH HHS R01 NS066927NINDS NIH HHS R01 NS095989
Abstract
Peripheral myelin protein 22 (PMP22) is highly expressed in myelinating Schwann cells of the peripheral nervous system.
Indexed as
Cell MembraneCharcot-Marie-Tooth DiseaseCysteineHumansLipid BilayersLipidsLiposomesMutationMyelin ProteinsRecombinant ProteinsCysteineLipid BilayersLipidsLiposomesMyelin ProteinsPMP22 protein, humanRecombinant ProteinsCharcot-Marie-Tooth DiseaseElectron MicroscopyMembraneMyelinNeuropathyPeripheral Myelin Protein 22Peripheral Nervous SystemPNSReconstitution
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.