ArticleOpen forum infectious diseases2017
Integrated Tuberculosis/Human Immunodeficiency Virus Community-Based Case Finding in Rural South Africa: Implications for Tuberculosis Control Efforts.
Article in Open forum infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Integrating HIV services and other health services: A systematic review and meta-analysis.PLoS medicine · 2021Pooled it
- Test and Treat TB: a pilot trial of GeneXpert MTB/RIF screening on a mobile HIV testing unit in South Africa.BMC infectious diseases · 2019Trial
- Evaluating community knowledge of tuberculosis preventive therapy in rural South Africa.BMC public health · 2025Article
- An Investigation of Risk Factors Associated with Tuberculosis Transmission in South Africa Using Logistic Regression Model.Infectious disease reports · 2022Article
- Community-based referral for tuberculosis preventive therapy is effective for treatment completion.PLOS global public health · 2022Article
- Feasibility of a community-based delivery model for HIV pre-exposure prophylaxis among bar patrons in rural South Africa.Journal of the International AIDS Society · 2021Article
- Mobility and structural barriers in rural South Africa contribute to loss to follow up from HIV care.AIDS care · 2021Article
- Leveraging HIV Care Infrastructures for Integrated Chronic Disease and Pandemic Management in Sub-Saharan Africa.International journal of environmental research and public health · 2021Article
- Mobile Device Usage by Gender Among High-Risk HIV Individuals in a Rural, Resource-Limited Setting.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2021Article
- Factors associated with low tuberculosis preventive therapy prescription rates among health care workers in rural South Africa.Global health action · 2021Article
- Opportunities for community health workers to contribute to global efforts to end tuberculosis.Global public health · 2020Review
- Article
- Synergism between diabetes and human immunodeficiency virus in increasing the risk of tuberculosis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2018Article
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundIntensive case finding is endorsed for tuberculosis (TB) control in high-risk populations. Novel case-finding strategies are needed in hard-to-reach rural populations with high prevalence of TB and human immunodeficiency virus (HIV).
methodsWe performed community-based integrated HIV and TB intensive case finding in a rural South African subdistrict from March 2010 to June 2012. We offered TB symptom screening, sputum collection for microbiologic diagnosis, rapid fingerstick HIV testing, and phlebotomy for CD4 cell count. We recorded number of cases detected and calculated population-level rates and number needed to screen (NNS) for drug-susceptible and -resistant TB.
resultsAmong 5615 persons screened for TB at 322 community sites, 91.2% accepted concurrent HIV testing, identifying 510 (9.9%) HIV-positive individuals with median CD4 count of 382 cells/mm
conclusionCommunity-based integrated intensive case finding is feasible and is high yield for drug-susceptible and -resistant TB and HIV in rural South Africa. Human immunodeficiency virus-negative tuberculosis predominated in this community sample, suggesting a distinct TB epidemiology compared with cases diagnosed in healthcare facilities. Increasing HIV/TB integrated community-based efforts and other strategies directed at both HIV-positive and HIV-negative tuberculosis may contribute to TB elimination in high TB/HIV burden regions.
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