ReviewJournal of ophthalmology2017
The Association between Adiposity and the Risk of Glaucoma: A Meta-Analysis.
Review in Journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Ocular and Systemic Risk Factors and Biomarkers for Primary Glaucoma: An Umbrella Review of Systematic Reviews With Meta-Analyses.Investigative ophthalmology & visual science · 2025Pooled it
- Role of excessive weight in intraocular pressure: a systematic review and meta-analysis.BMJ open ophthalmology · 2023Pooled it
- Pooled it
- The impact of obesity or overweight on the risk of glaucoma: a meta-analysis.Frontiers in medicine · 2026Article
- Joint trajectories of obesity and depressive symptoms and risk of incident glaucoma: a 16-year prospective cohort study from the Health and Retirement Study.Frontiers in aging neuroscience · 2026Article
- Review
- Integrating Deep Learning with Electronic Health Records for Early Glaucoma Detection: A Multi-Dimensional Machine Learning Approach.Bioengineering (Basel, Switzerland) · 2024Article
- Causal factors in primary open angle glaucoma: a phenome-wide Mendelian randomisation study.Scientific reports · 2023Article
- Automated Detection of Glaucoma With Interpretable Machine Learning Using Clinical Data and Multimodal Retinal Images.American journal of ophthalmology · 2021Article
- Is Obesity a Risk or Protective Factor for Open-Angle Glaucoma in Adults? A Two-Database, Asian, Matched-Cohort Study.Journal of clinical medicine · 2021Article
- Association of body mass index with longitudinal rates of retinal atrophy in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2020Observational
- Ocular blood flow as a clinical observation: Value, limitations and data analysis.Progress in retinal and eye research · 2020Article
- Association between metabolic risk factors and optic disc cupping identified by deep learning method.PloS one · 2020Article
- Profile and management outcomes of glaucoma cases at Qassim University Hospital.International journal of health sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis meta-analysis was conducted to determine the potential association between adiposity and glaucoma incidence. MATERIALS AND
methodsA comprehensive literature search was performed in PubMed and ISI Web of Science. A meta-analysis was conducted using STATA software.
resultsFifteen eligible studies involving 2,445,980 individuals were included to investigate the association between adiposity and glaucoma incidence. The relative risks (RRs) were pooled with 95% confidence intervals (CI) by using a random-effects model. The pooled RR between adiposity and elevated intraocular pressure (IOP) was 1.73 (95% CI, 1.18-2.54), whereas that between adiposity and open-angle glaucoma (OAG) was 0.97 (95% CI, 0.83-1.13). The pooled RR between abdominal adiposity and glaucoma was 1.28 (95% CI, 1.15-1.41), whereas that between general adiposity and glaucoma was 1.09 (95% CI, 0.87-1.37). Results of subgroup analysis by sex indicated the association between adiposity and glaucoma in the female group (RR, 1.31; 95% CI, 1.05-1.64), but not in the male group (RR, 1.11; 95% CI, 0.77-1.60). The pooled RR of cohort studies and cross-sectional studies were 1.00 (95% CI, 0.84-1.20) and 1.22 (95% CI, 0.89-1.66), respectively.
conclusionsAdiposity has a higher risk of elevated IOP, and abdominal adiposity has a positive association with glaucoma, especially in female patients.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.