Evidence map›Paper›PMID 28694944›Full record

ArticleChemical science2015

Integration of an anti-tumor drug into nanocrystalline assemblies for sustained drug release.

Xiangrui Yang, Shichao Wu, Yang Li, Yu Huang, Jinyan Lin, Di Chang, Shefang Ye, Liya Xie, Yuan Jiang, Zhenqing Hou

Abstract read
In one paragraph

Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiangrui YangInstitute of Soft Matter and Biomimetics , College of Materials , Xiamen University , Xiamen 361005 , China . Email: houzhenqing@xmu.edu.cn ; Email: yuan.jiang@xmu.edu.cn.
Shichao WuInstitute of Soft Matter and Biomimetics , College of Materials , Xiamen University , Xiamen 361005 , China . Email: houzhenqing@xmu.edu.cn ; Email: yuan.jiang@xmu.edu.cn.
Yang LiInstitute of Soft Matter and Biomimetics , College of Materials , Xiamen University , Xiamen 361005 , China . Email: houzhenqing@xmu.edu.cn ; Email: yuan.jiang@xmu.edu.cn.
Yu HuangInstitute of Soft Matter and Biomimetics , College of Materials , Xiamen University , Xiamen 361005 , China . Email: houzhenqing@xmu.edu.cn ; Email: yuan.jiang@xmu.edu.cn.
Jinyan LinInstitute of Soft Matter and Biomimetics , College of Materials , Xiamen University , Xiamen 361005 , China . Email: houzhenqing@xmu.edu.cn ; Email: yuan.jiang@xmu.edu.cn.
Di ChangInstitute of Soft Matter and Biomimetics , College of Materials , Xiamen University , Xiamen 361005 , China . Email: houzhenqing@xmu.edu.cn ; Email: yuan.jiang@xmu.edu.cn.
Shefang YeInstitute of Soft Matter and Biomimetics , College of Materials , Xiamen University , Xiamen 361005 , China . Email: houzhenqing@xmu.edu.cn ; Email: yuan.jiang@xmu.edu.cn.
Liya XieThe First Affiliated Hospital of Xiamen University , Xiamen University , Xiamen 361003 , China.
Yuan JiangInstitute of Soft Matter and Biomimetics , College of Materials , Xiamen University , Xiamen 361005 , China . Email: houzhenqing@xmu.edu.cn ; Email: yuan.jiang@xmu.edu.cn.
Zhenqing HouInstitute of Soft Matter and Biomimetics , College of Materials , Xiamen University , Xiamen 361005 , China . Email: houzhenqing@xmu.edu.cn ; Email: yuan.jiang@xmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delicate mesoscopic architectures, bearing complex forms with multiple hierarchy levels, lead to significant functions in biogenic minerals. Herein, a bio-inspired approach was developed to fabricate comet-shaped assemblies of an anti-tumor drug - 10-hydroxycamptothecin (HCPT). The anti-solvent co-precipitation of HCPT and the excipient - PEG-

Identifiers

PMID28694944
PMCPMC5483847

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.