ReviewComputational and structural biotechnology journal2017
Regulation of Metabolic Pathways by MarR Family Transcription Factors.
Review in Computational and structural biotechnology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
54 citing papers in PubMed, 91 citations in OpenAlex.
- TagR, a newly identified member of the MarR family of transcriptional regulators, represses the NRPS operon inMicrobiology spectrum · 2026Article
- Modulation of rob expression accelerates development of antibiotic resistance in Yersinia enterocolitica.Nucleic acids research · 2026Article
- Regulation of Aromatic Compounds and Environmental Stimuli Response by the MarR Family Regulator AesR inMicroorganisms · 2026Article
- 2''-O-galloylhyperin as a novel adjuvant to reduce imipenem resistance in multidrug-resistant Pseudomonas aeruginosa: transcriptome-based mechanism of iron homeostasis disruption.BMC microbiology · 2026Article
- Development of phage-resistantFood chemistry: X · 2026Article
- Article
- A Dual-Receptor System MediatesJournal of agricultural and food chemistry · 2026Article
- DNA-bound structure of Clostridioides difficile heme-sensing HsmR gives insight on how the unique dimer mode governs DNA specificity in MarR transcriptional regulators.Nucleic acids research · 2025Article
- The MarR family transcription factor SlyA senses iron and respiratory status in enteric bacteria.mBio · 2025Article
- Proteomic and metabolomic responses of priority bacterial pathogens to subinhibitory concentration of antibiotics.npj antimicrobials and resistance · 2025Article
- Redox control of antibiotic biosynthesis.mBio · 2025Article
- Metabolism of Terephthalic Acid by a Novel Bacterial Consortium Produces Valuable By-Products.Microorganisms · 2025Article
- An endoribonuclease of the YicC-like family delays sporulation via sRNA degradation in Clostridioides difficile.Nucleic acids research · 2025Article
- SydR, a redox-sensing MarR-type regulator ofmBio · 2024Article
- Structural basis of transcriptional regulation by UrtR in response to uric acid.Nucleic acids research · 2024Article
- Regulation of bacterial virulence genes by PecS family transcription factors.Journal of bacteriology · 2024Review
- Heterologous expression of the Oenococcus oeni two-component signal transduction response regulator in the Lactiplantibacillus plantarum WCFS1 strain enhances acid stress tolerance.BMC microbiology · 2024Article
- Review
- Quantitative Proteomics Analysis Reveals the Effect of a MarR Family Transcriptional RegulatorBiology · 2023Article
- MarR Family Transcriptional Regulators and Their Roles in Plant-Interacting Bacteria.Microorganisms · 2023Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Bacteria have evolved sophisticated mechanisms for regulation of metabolic pathways. Such regulatory circuits ensure that anabolic pathways remain repressed unless final products are in short supply and that catabolic enzymes are not produced in absence of their substrates. The precisely tuned gene activity underlying such circuits is in the purview of transcription factors that may bind pathway intermediates, which in turn modulate transcription factor function and therefore gene expression. This review focuses on the role of ligand-responsive MarR family transcription factors in controlling expression of genes encoding metabolic enzymes and the mechanisms by which such control is exerted. Prospects for exploiting these transcription factors for optimization of gene expression for metabolic engineering and for the development of biosensors are considered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.